Wyo. Code R. 048-0035-1
Effective Date: 01/13/2000 to 04/28/2008
Rule Type: Superceded Rules & Regulations
Reference Number: 048.0035.1.01132000
Section 1. Authority. The statutory authority for these regulations is contained in W.S. 35-4-801 and 35-4-802. The Statute and Regulations are administered by the Department of Health.
Section 2. Definition. Specific genetic and metabolic tests to be done in Wyoming as determined by the committee designated in 35-4-801, section (b) are as follows:
(a) "Phenylketonuria (PKU)". Genetic metabolic disorder characterized by abnormal phenylalanine metabolism. (b) "Hypothyroidism". Metabolic disorder caused by inadequate production or secretion of thyroid hormone. (c) "Galactosemia". Genetic metabolic disorder characterized by abnormal galactose metabolism. (d) "Hemoglobinopathies". Group of genetic diseases including sickle cell anemia characterized by the abnormal production and function of hemoglobin. (e) "Cystic Fibrosis". Genetic disorder characterized by dysfunction of one or more exocrine systems. (f) "Biotinidase Deficiency". Genetic metabolic disorder characterized by abnormal biotinidase production. (g) Any other genetic or metabolic disease for which testing may hereinafter be required on the basis of action taken by the designated committee.
Section 3. Consent for Screening. Consent for screening can be from natural parents, either custodial parent, a sole guardian, single parent having custody or prospective adoptive parents or parent of whom the child's custody has been released. No test shall be performed until the written consent of the natural parents, or the custodial parent or the guardian or the adoptive parents is obtained. If any parent or guardian objects to the mandatory testing for a child, then his objection shall be in written form and the child is exempt from such testing.
Section 4. Blood Collection.
(a) The optimal timing for newborn screening in full-term healthy infants is between 48 and 72 hours. In early discharge the blood should be collected as late as possible before discharge but no later than 72 hours of age. (b) Any newborn infants requiring exchange transfusions shall have the blood sample for these tests taken prior to the exchange transfusion.
(c) If the child is not born in a hospital, the attending physician, midwife, or person attending the delivery shall arrange to have the blood sample taken by a physician, hospital personnel, laboratory personnel, or local public health representative.
(d) If the child is to be transferred to another hospital, the transferring hospital shall conduct the newborn screen prior to discharge or make arrangements with the receiving hospital to conduct the screen.
(e) Collection forms provided by the Department of Health shall be completed for each blood sample. Each sample shall be sent to the regional laboratory within 24 hours from the time that the sample was collected.
(f) Hospitals will record numbers of births and numbers of infants screened. The hospital record will include the number of infants not screened and the reason why the screening was not performed. Reports will be made to the Department of Health on request, not less than once yearly.
(g) The Department of Health will provide information brochures and consent forms on request.
Section 5. Second Test. If the initial screen was conducted prior to 24 hours of age, a second (or follow-up) blood sample should be collected when the infant is approximately ten (10) days to two (2) weeks of age and may be collected at a hospital laboratory, physician’s office or local public health facility.
Positive or questionable results will be reported to the infant’s physician as well as the Department of Health.
Section 6. Fees. Upon consultation with the designated committee, the Department of Health may establish a fee-for-service mechanism to cover the cost of conducting the screening of newborn infants for inborn errors of metabolism.