S.C. Code Ann. § 44-43-340
(A) Subject to subsections (B) and (C) and unless barred by Section 44-43-330 or 44-43-335, an anatomical gift of a decedent's body or part for purpose of transplantation, therapy, research, or education may be made by any member of the following classes of persons who is reasonably available, in the order of priority listed:
(2) a spouse of the decedent unless the spouse and the decedent are separated pursuant to one of the following: