S.C. Code Ann. § 40-47-1010
A physician assistant's license must be renewed on or before the first of January of each licensure period. Upon payment of the nonrefundable renewal fee provided for in Section 40-47-1015 and submission of documentation that the physician assistant certificate with the National Commission on Certification of Physician Assistants, Inc., or its successor, is active and current, the board shall renew the physician assistant's license.