S.C. Code Ann. § 20-4-30
The Family Court has jurisdiction over all proceedings under this chapter except that, during nonbusiness hours or at other times when the court is not in session, the petition may be filed with a magistrate. The magistrate may issue an order of protection granting only the relief provided by Section 20-4-60 (a) (1).
Actions for an order of protection shall be filed in the county (a) in which the respondent resides at the time of the commencement of the action, (b) in which the petitioner resides if the respondent is a nonresident or after due diligence cannot be found, or (c) in which the parties last resided together unless the petitioner is a nonresident in which case it must be brought in the county in which the respondent resides.