The amendment filed [1] contains a data file on read-only optical disc that is not in an ASCII file format or an XML file format (only for a "Sequence Listing XML" submission). File [2] is not in an ASCII format or an XML file format. Applicant is required to resubmit file(s) in ASCII format or XML format as required by 37 CFR 1.52(e)(3)(iii). No new matter may be introduced in presenting the file(s) in ASCII format or XML format.

Examiner Note:

1. This form paragraph must be used whenever a data file ("Large Tables," a "Computer Program Listing Appendix," a "Sequence Listing," or a "Sequence Listing XML" (as applicable) is submitted in a non-ASCII file format or a non-XML file format (as applicable). The file may be in a file format that is proprietary, e.g., a Microsoft Word, Excel or Word Perfect file format; and/or the file contains non-ASCII characters or fails to comply with the requirements for a "Sequence Listing XML" submitted under 1.52(e).

2. In bracket 1, insert the date of the amendment.

3. In bracket 2, insert the name of the file and whether the file is a non-text proprietary file format and/or contains non-ASCII characters and/or contains non-XML characters (as applicable).