This application contains a data file on a read-only optical disc that is not in an ASCII file format or an XML file format (only for "Sequence Listing XML"). See 37 CFR 1.52(e). File [1] is not in an ASCII format or XML format. Applicant is required to resubmit file(s) in ASCII format or XML format. No new matter may be introduced in presenting the file(s) in ASCII format or XML format.

Examiner Note:

1. This form paragraph must be used to indicate whenever a data file ("Large Table", "Computer Program Listing Appendix" or "Sequence Listing") is submitted in a non-ASCII file format. The file may be in a file format that is proprietary, e.g., a Microsoft Word, Excel or Word Perfect file format; and/or the file may contain non-ASCII characters.

2. In bracket 1, insert the name of the file and whether the file is a non-text proprietary file format and/or contains non-ASCII characters.