PURPOSE: This rule establishes requirements for prospective drug utilization review prior to dispensing a prescription or medication order.

1. (1) Prospective Drug Review.

   1. (A) Prior to dispensing or otherwise approving medication for patient use, pharmacists shall use their professional judgment to review available patient records to assess therapeutic appropriateness.
   2. (B) The pharmacist shall take appropriate steps within their professional judgment to address or resolve identified therapeutic appropriateness issues. Prospective drug review may only be performed by a pharmacist or an intern pharmacist working under the supervision of a Missouri licensed pharmacist.

AUTHORITY: sections 338.100 and 338.280, RSMo 2016, and sections 338.035 and 20 CSR 2220-2 338.140, RSMo Supp. 2020.* Original rule filed Sept. 1, 2020, effective Feb. 28, 2021.

*Original authority: 338.035, RSMo 1990, amended 1993, 1995, 2007, 2020; 338.100, RSMo 1939, amended 1971, 1990, 1997, 1999, 2010, 2016; 338.140, RSMo 1939, amended 1981, 1989, 1997, 2011, 2019; and 338.280, RSMo 1951, amended 1971, 1981.