RELATES TO:

KRS 230.215, 230.225, 230.240, 230.260, 230.265, 230.290, 230.320, 230.370

STATUTORY AUTHORITY:

KRS 230.215(2), 230.225, 230.240(2), 230.260, 230.320, 230.370

NECESSITY, FUNCTION, AND CONFORMITY:

KRS 230.215(2) authorizes the Kentucky Horse Racing and Gaming Corporation (the "corporation") to promulgate administrative regulations prescribing conditions under which all legitimate horse racing and wagering thereon is conducted in Kentucky. KRS 230.240(2) requires the corporation to promulgate administrative regulations restricting or prohibiting the administration of drugs or stimulants or other improper acts to horses prior to the horse participating in a race. This administrative regulation establishes the drug classification schedule in effect in Kentucky for permitted drugs, medications, and substances that may be administered to race horses competing in Kentucky.

1. Section 1. The Kentucky Horse Racing and Gaming Corporation Uniform Drug, Medication, and Substance Classification Schedule.

   1. (1) This administrative regulation shall establish the respective classifications of all substances contained herein.

   2. (2)

      1. (a) Class A drugs, medications, and substances are those that:

         1. 1. Have the highest potential to influence performance in the equine athlete, regardless of their approval by the United States Food and Drug Administration; or
         2. 2. Lack approval by the United States Food and Drug Administration, but have pharmacologic effects similar to certain Class B drugs, medications, or substances that are approved by the United States Food and Drug Administration.
      2. (b) Class A shall include: AcecarbromalAcetophenazineAdinazolamAlcuroniumAlfentanilAlmotriptanAlphaprodineAlpidemAlprazolamAlprenololAlthesinAminorexAmisulprideAmitriptylineAmobarbitalAmoxapineAmperozideAmphetamineAmyl nitriteAnileridineAnilopamApomorphineAprobarbitalArecolineAtracuriumAtomoxetineAzacylonolAzaperoneBarbitalBarbituratesBemegrideBenazeprilBenperidolBentazepamBenzactizineBenzoctamineBenzonatateBenzphetamineBenztropineBenzylpiperazineBethanidineBiperidenBiriperoneBitolterolBolasteroneBoldioneBrimondineBromazepamBromfenacBromisovalumBromocriptineBromperidolBrotizolamBufexamacBupivacaineBuprenorphineBuspironeBupropionButabartitalButacaineButalbitalButanilicaineButaperazineButoctamideCalusteroneCamazepamCannabinoids, SyntheticCaptadiameCarazololCarbidopaCarbromalCarfentanilCarphenazineCarpipramineCathinoneChloral betaineChloral hydrateChloraldehydeChloraloseChlordiazepoxideChlorhexadolChlormezanoneChloroformChloroprocaineChlorproethazineChlorpromazineChlorprothixeneCimaterolCitalopramCllibucaineClobazamClocapramineClomethiazoleClomipramineClonazepamClorazepateClormecaineClostebolClothiapineClotiazepamCloxazolamClozapineCobratoxinCocaineCodeineConorphoneConotoxinCorticaineCrotetamideCyamemazineCyclandelateCyclobarbitalDarbepoetinDecamethoniumDehydrochloromethy-testosteroneDelorazepamDemoxepamDermorphinDesipramineDesoxymethyl-testosteroneDextromoramideDezocineDiamorphineDichloralphenazoneDiethylpropionDiethylthiambuteneDihydrocodeineDimeflineDiprenorphineDivalproexDixyrazineDonepezilDopamineDoxacuriumDoxapramDoxazosinDoxefazepamDoxepinDroperidolDuloxetineEletriptanEnalaprilEnciprazineEndorphinsEnkephalinsEphedrineEpibatidineEpinephrineErgaloid MesylatesErthritol tetranitrateErythropoietinEszopicloneEstazolamEthamivanEthanolEthchlorvynolEthinamateEthoheptazineEthopropazineEthosuximideEthylisobutrazineEthylmorphineEthylnorepinephrineEthylphenidateEtidocaineEtifoxinEtizolamEtodroxizineEtomidateEtorphine HCLFenarbamateFenfluramineFentanylFluanisoneFludiazepamFlunitrazepamFluopromazineFluoresoneFluoxetineFlupenthixolFlupirtineFlurazepamFluspirileneFlutoprazepamFluvoxamineFormeboloneFosinoprilFurzabolGalantamineGallamineGepironeGestrinoneGlutethimideGuanadrelGuanethidineHalazepamHaloperidolHaloxazolamHemoglobinglutamersHemopureHexafluoreniumHexobarbitalHomophenazineHydrocodoneHydromorphoneHydroxyamphetamineIbomalIloprostImipramineInositolTrispyrophosphateIpsapironeIrbesartenIsocarboxazidIsomethadoneIsoproterenolKetazolamKetorolacLamotrigineLenperoneLevodopaLevomethorphanLevorphanolLisinoprilLithiumLobelineLofentanilLoflazepate, EthylLoprazolamLorazepamLormetazepamLoxapineMabuterolMaprotilineMazindolMebutamateMeclofenoxateMedazepamMeldoniumMelperoneMemantineMeparfynolMepazineMeperidineMephenoxaloneMephentermineMephenytoinMephobarbitalMeprobamateMesoridazineMestanoloneMesteroloneMetaclazepamMetaraminolMetazocineMethachlolineMethadoneMethamphetamine, when detected exclusively as d-methamphetamine or in combination with l-methamphetamineMethandriolMethandrostenoloneMethaqualoneMetharbitalMethasteroneMethcathinoneMethenoloneMethixeneMethohexitalMethotrimeprazineMethoxamineMethoxyphenamine3-MethoxytyramineMethyl-1-testosteroneMethylandriostenediolMethyldienoloneMethyldopaMethyleneDioxypyrovalene(MDPV; 3,4Methylenedioxy-pyrovalerone)MethylhexaneamineMethylnortestosteroneMethylphenidateMethyprylonMetocurineMetomidateMetoponMexazolamMirtazapineMivacuriumModafinilMolindoneMoperoneMorphineMosapramineMuscarineNaepaineNalbuphineNalorphineNebivololNefazodoneNefopamNikethamideNimetazepamNitrazepamNorbolethoneNorclostebolNordiazepamNorepinephrineNorethandroloneNortriptylineNylidrinOlanzapineOlmesartanOxaboloneOxazepamOxazolamOxcarbazepineOxilofrineOxprenololOxycodoneOxymesteroneOxymorphoneOxypertinePaliperidonePancuroniumPapaverineParaldehydeParamethadionePargylineParoxetinePemolinePenfluridolPentaerythritolPentobarbitalPentylenetetrazolPerazinePerfluorocarbonsPerfluorodecahydro-naphthalenePerfluorodecalinPerfluorooctylbromidePerfluorotripro-pylaminePericiazinePerindoprilPerlapinePerphenazinePhenaglycodolPhenazocinePhencyclidinePhendimetrazinePhenelzinePhenmetrazinePhenobarbitalPhenterminePhysostigminePicrotoxinPiminodinePimozidePinazepamPipamperonePipecuroniumPipequalinePiperacetazinePiperocainePipotiazinePipradrolPiquindonePiritramidePrazepamProcaterolProchlorperazinePropanididPropiomazinePropionylpromazinePropiramPropofolPropoxycaineProstanozolProthipendylProtokylolProtriptylineProxibarbitalPyrithyldioneQuazipamQuetiapineQuinapril / QuinaprilatQuinboloneRacemethorphanRacemorphanRacloprideRactopamineRamipril / RamiprilatRemifentanilRemoxiprideRilmazafoneRisperidoneRitanserinRivastigmineRocuroniumRopivacaineSecobarbitalSelegilineSertralineSildenafilSnake VenomsSomatremSomatropinSpiclomazineSpiperoneSpirapril / SpiraprilatStenboloneSuccinylcholineSufentanilSulfondiethylmethaneSulfonmethaneSulforidazineSulpirideSultoprideTadalasilTalbutalTandospironeTemazepamTerazosinTetrabenazineTetracaineTetrahydrogestrinoneTetrazepamThebaineThialbarbitalThiamylalThiethylperazineThiopentalThiopropazateThioproperazineThioridazineThiothixeneTiaprideTiletamineTimiperoneTofisopamTopirimateTorsemideTranylcypromineTrazodoneTretoquinolTriazolamTribromethanolTricaineTrichloroethanolTricholoethyleneTriclofosTrifluomeprazineTrifluoperazineTrifluperidolTriflupromazineTrihexylphenidylTrimethaphanTrimipramineTubocurarineTybamateUrethaneValerenic AcidValnoctamideVardenafilVenlafaxineVeraliprideVercuroniumViloxazineVinbarbitalVinylbitalZaleplonZiconotideZilpaterolhydrochlorideZiprasidoneZolazepamZolpidemZopicloneZotepineZuclopenthixol

   3. (3)

      1. (a) Class B drugs, medications, and substances are those that:

         1. 1. Are approved by the United States Food and Drug Administration and have a high potential to influence performance in the equine athlete, but less potential than Class A drugs, medications, and substances that are classified at that level because they have the highest potential to influence performance; or
         2. 2. Lack approval by the United States Food and Drug Administration, but have pharmacologic effects similar to certain Class C drugs, medications, or substances that are approved by the United States Food and Drug Administration.
      2. (b) Class B shall include: 2-AminoheptaneAcebutololAcepromazineAcetanilidAcetophenetidinAdrenochromemonosemicarbazonesalicylateAlbuterolAlclofenacAldosteroneAmbenoniumAmbroxolAmilorideAminophyllineAminopyrineAmiodaroneAmisometradineAmitrazAmlodipineAmrinoneAnisotropineAntipyrineApazoneAprindineArformoterolArticaineAtenololAtropineBaclofenBendroflumethiazideBenoxaprofenBenzocaineBenzthiazideBepridilBetaxololBisoprololBoldenoneBretyliumBromhexineBromodiphenhydramineBrompheniramineBumetanideButorphanolButoxycaineCaffeineCandesartanCaptoprilCarbacholCarbamezapineCarbazochromeCarbinoxamineCarisoprodolCarprofenCarteololCarticaineCarvedilolCelecoxibChlormerodrinChlorothiazideChlorpheniramineChlorthalidoneChlorzoxazoneCilostazolClanobutinClemastineClenbuterolClidiniumClofenamideClonidineColchicineCyclizineCyclobenzaprineCyclothiazideCycrimineCyproheptadineDanazolDeracoxibDetomidineDextromethorphanDextropropoxypheneDiazepamDiazoxideDibucaineDiflunisalDigitoxinDigoxinDihydroergotamineDiltiazemDimethisoquinDiphenhydramineDiphenoxylateDipyridamoleDisopyramideDobutamineDoxylamineDromstanoloneDyphyllineEdrophoniumEltenacEnalaprilErgotamineEsmololEtamiphyllineEtanerceptEthacrynic acidEthotoinEthylestrenolEtodolacFelbamateFelodipineFenbufenFenclozic acidFenoldopamFenoprofenFenoterolFenspirideFentiazacFlecainideFloctafenineFlufenamic acidFlumethiazideFlunarizineFluoroprednisoloneFluoxymesteroneFluphenazineFlurbiprofenFormoterolFosphenytoinGabapentinGuanabenzHeptaminolHexocycliumHexylcaineHomatropineHydralazineHydrochlorthiazideHydroflumethiazideHydroxyzineIbutilideIndomethacinInfliximabIpratropiumIsoetharineIsomethepteneIsopropamideIsosorbide dinitrateIsoxicamIsradipineKebuzoneKetamineL-methamphetamine, when detected by itself and not in combination with d-methamphetamineLabetalolLevamisoleLevobunololLidocaineLoperamideLosartanMecamylamineMeclizineMedetomidineMefenamic acidMelMepenzolateMephenesinMepivacaineMerallurideMerbaphenMercaptomerinMercumatilinMersalylMetaproterenolMetaxaloneMethanthelineMethapyrileneMethdilazineMethosuxamideMethotrexateMethscopolamineMethylatropineMethylchlorthiazideMethysergideMethyltestosteroneMetiamideMetolazoneMetoprololMexilitineMibefradilMiboleroneMidazolamMidodrineMilrinoneMinoxidilMoexipriloxicamNadolNaloxoneNaltrexoneNandroloneNaphazolineNaratriptanNeostigmineNicardipineNifedipineNiflumic acidNimesulideNimodipineNitroglycerinNortestosteroneOrphenadrineOxandroloneOxaprozinOxymetazolineOxymetholoneOxyphencyclimineOxyphenoniumPenbutololPentazocinePergolidePhenacemidePhenoxybenzaminePhensuximidePhentolaminePhenylephrinePhenylpropanolaminePhenytoinPindololPirbuterolPiretanidePiroxicamPolythiazidePrazosinPrilocainePrimidoneProcainamideProcaineProcyclidinePromazinePromethazinePropafenonePropanthelinePropentophyllinePropranololPropylhexedrinePseudoephedrinePyridostigminePyrilamineQuinidineReserpineRitodrineRizatriptanRofecoxibRomifidineSalmeterolScopolamineSibutramineSotalolSpironalactoneStanozololStrychnineSumatriptanTelmisartinTenoxicamTepoxalinTerbutalineTerfenadineTestolactoneTestosteroneTetrahydrozolineTheobromineTheophyllineThiosalicylateThiphenamilTiaprofenic acidTimololTocainideTolazolineTolmetinTramadolTrandolaprilTrenboloneTriamtereneTridihexethylTrimeprazineTrimethadioneTripelennamineTriprolidineValdecoxibValsartanVedaprofenVerapamilXylazineXylometazolineYohimbineZolmitriptanZomepiracZonisamide

   4. (4)

      1. (a) Class C drugs, medications, and substances are those that:

         1. 1. Are approved by the United States Food and Drug Administration and have a lesser potential to influence performance in the equine athlete than Class A drugs, medications, and substances and those Class B drugs, medications, and substances that are classified at that level because they have a high potential to influence performance and are approved by the United States Food and Drug Administration; or
         2. 2. Lack approval by the United States Food and Drug Administration, but have pharmacologic effects similar to certain Class D drugs, medications, or substances that are approved by the United States Food and Drug Administration.
      2. (b) Class C shall include: AcenocoumarolAcetaminophenAcetazolamideAcetylsalicylic acidAlclometasoneAmcinonideAminocaproic acidBeclomethasoneBenoxinateBetamethasoneBethanecholBudesonideButambenCamphorCetirizineChlorophenesinChloroquineCiclesonideClobetasolClocortoloneCortisoneCyclomethylcaineDantroleneDembroxolDeoxycorticosteroneDesonideDesoximetasoneDexamethasoneDibucaineDichlorphenamideDiclofenacDiflorasoneDiflucortoloneDimethylsulfoxideDiphenadioneDipyroneDyclonineErgonovineEthoxzolamideEthylaminobenzoateFexofenadineFirocoxibFludrocortisoneFlumethasoneFlunisolideFlunixinFluocinoloneFluocinonideFluorometholoneFluprednisoloneFlurandrenolideFluticasoneFurosemideGlycopyrrolateGuaifenesinHalcinonideHalobetasolHydrocortisoneIbuprofenIsoflupredoneKetoprofenLetosteineLoratidineMeclofenamic acidMedrysoneMesalamineMethazolamideMethocarbamolMethylergonovineMethylprednisoloneMetoclopramideMometasoneMontelukastN-butylscopolamineNabumetoneNaproxenOlsalazineOxyphenbutazoneParamethasonePhenylbutazonePirenzapinePramoxinePrednisolonePrednisoneProbenecidProparacaineSalicylamideSalicylateSulfasalazineSulindacTranexamic acidTriamcinolone acetonideTrichlormethiazideZafirlukastZeranolZileuton

   5. (5)

      1. (a) Class D drugs, medications, and substances are those that:

         1. 1. Have a lesser potential to influence performance in the equine athlete than Class A and B drugs, medications, and substances or those Class C drugs, medications, and substances that are classified at that level because they have a lesser potential to influence performance and are not approved by the United States Food and Drug Administration; or
         2. 2. Have a lesser potential to influence performance in the equine athlete than any Class A, B, or C drugs, medications or substances.
      2. (b) Class D shall include: AnisindioneCimetidineCromolynDicumarolEsomeprazoleFamotidineIsoxsuprineLansoprazoleMisoprostolNedocromilNizatidineOmeprazolePantoprazolePentoxyfyllinePhenindionePhenprocoumonPolyethylene glycolRabeprazoleRanitidineWarfarin

FILED WITH LRC: July 1, 2024 (45 Ky.R. 2001; 3170; eff. 5-31-2019; 46 Ky.R. 2839; eff. 8-25-2020; 47 Ky.R. 2159; eff. 10-5-2021; 49 Ky.R. 2016; eff. 12-5-2023; TAm eff. 7-1-2024.)