D.C. Mun. Regs. tit. 22-C, § 5404
5404.1 A licensee shall obtain the approval of the Board by filing an application for a substantial change, if not initially approved as part of the licensee's initial application, prior to:
(1) Changing or expanding its location;
(2) Increasing the facility's plant capacity or physical plant count to another tier, if a cultivation center;
(3) Adding a safe-use treatment facility or summer garden;
(4) Extracting medical cannabis if not previously permitted or authorized;
(5) Increasing the hours of operation, delivery, or the hours of sale, service, or consumption of cannabis at the premises, the safe-use treatment facility, or the summer garden; or
(6) Increasing the physical occupancy or capacity of the premises, the safe-use treatment facility, or the summer garden or allowing or permitting more persons than permitted by the Board.
SOURCE: Emergency and Third Proposed Rulemaking published at 58 DCR 3299 (April 15, 2011)[EXPIRED]; as amended by Emergency and Fourth Proposed Rulemaking published at 58 DCR 7207 (August 12, 2011)[EXPIRED]; as amended by Final Rulemaking published at 58 DCR 10128, 10185 (December 2, 2011); as amended by Final Rulemaking published at 60 DCR 10061 (July 12, 2013); as amended by Final Rulemaking published at 64 DCR 13490 (December 29, 2017); as amended by Final Rulemaking published at 66 DCR 10217 (August 9, 2019); as amended by Final Rulemaking published at 71 DCR 002388 (March 8, 2024); as amended by Final Rulemaking published at 73 DCR 002136 (February 20, 2026).