21 C.F.R. § 558.248 – Erythromycin.

(a) Specifications. Type A medicated articles containing 92.5 grams per pound erythromycin (as the thiocyanate salt).
(b) Sponsor. See No. 061133 in § 510.600(c) of this chapter.
(c) Related tolerances. See § 556.230 of this chapter.
(d) Special considerations.
1. (1) Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian. See § 558.6 for additional requirements.
2. (2) The expiration date of VFDs for erythromycin medicated feeds must not exceed 6 months from the date of issuance. VFDs for erythromycin shall not be refilled.

(e) Conditions of use—(1) Chickens—

Erythromycin in grams/ton	Indications for use	Limitations	Sponsor
(i) 92.5	Chickens: As an aid in the prevention of chronic respiratory disease during periods of stress	Feed for 2 days before stress and 3 to 6 days after stress. Withdraw 24 hours before slaughter	061623
(ii) 92.5	Chickens: As an aid in the prevention of infectious coryza	Feed for 7 to 14 days. Withdraw 24 hours before slaughter	061623
(iii) 185	Chickens: As an aid in the prevention and reduction of lesions and in lowering severity of chronic respiratory disease (CRD)	Feed for 5 to 8 days. Withdraw 48 hours before slaughter. Do not use in birds producing eggs for food	061623

(2) Turkeys—

Erythromycin thiocyanate in grams/ton	Combination in grams/ton	Indications for use	Limitations	Sponsor
(i) 92.5		Turkeys: As an aid in the prevention of chronic respiratory disease during periods of stress	Feed for 2 days before stress and 3 to 6 days after stress	061623
(ii) 185		Turkeys: As an aid in the prevention and reduction of lesions and in lowering severity of chronic respiratory disease (CRD)	Feed for 5 to 8 days. Do not use in birds producing eggs for food	061623

[41 FR 10999, Mar. 15, 1976, as amended at 45 FR 56799, Aug. 26, 1980; 49 FR 31281, Aug. 6, 1984; 51 FR 7397, Mar. 3, 1986; 52 FR 2684, Jan. 26, 1987; 54 FR 12189, Mar. 24, 1989; 66 FR 14074, Mar. 9, 2001; 68 FR 4915, Jan. 31, 2003; 79 FR 10982, Feb. 27, 2014; 81 FR 36790, June 8, 2016; 81 FR 95004, Dec. 27, 2016; 84 FR 8975, Mar. 13, 2019]