21 C.F.R. § 556.113 – Ceftiofur.

(a) Acceptable daily intake and acute reference dose—(1) Acceptable daily intake (ADI). The ADI for total residue of ceftiofur is 30 µg/kg of body weight per day.
(2) Acute reference dose (ARfD). The ARfD for total residue of ceftiofur is 0.830 mg/kg of body weight.
(b) Tolerances. The tolerances for desfuroylceftiofur (marker residue) are:
1. (1) Cattle.
  1. (i) Kidney (target tissue): 0.4 ppm.
  2. (ii) Liver: 2 ppm.
  3. (iii) Muscle: 1 ppm.
  4. (iv) Milk: 0.1 ppm.
2. (2) Chickens and turkeys. Edible tissues (excluding eggs): Not required.
3. (3) Goats.
  1. (i) Kidney (target tissue): 8 ppm.
  2. (ii) Liver: 2 ppm.
  3. (iii) Muscle: 1 ppm.
  4. (iv) Milk: 0.1 ppm.
4. (4) Sheep. Edible tissues (excluding milk): Not required.
5. (5) Swine.
  1. (i) Kidney (target tissue): 0.25 ppm.
  2. (ii) Liver: 3 ppm.
  3. (iii) Muscle: 2 ppm.
(c) Related conditions of use. See §§ 522.313a, 522.313b, 522.313c, and 526.313 of this chapter.