1. (1) A sample and related batch of cannabinoid product fails quality assurance testing for residual solvents if the results exceed the limits provided in Table 4 unless the solvent is:

   1. (a) a component of the product formulation;
   2. (b) listed as an ingredient; and

   3. (c) generally considered to be safe for the intended form of use.

      TABLE 4List of Solvents and Action LevelsSolventChemical Abstract ServiceAction level(CAS)Registry numberPpm1,2 Dimethoxyethane110-71-41001,4 Dioxane123-93801-Butanol71-36-35,0001-Pentanol71-41-05,0001-Propanol71-23-85,0002-Butanol78-92-25,0002-Butanone78-93-35,0002-Ethoxyethanol110-80-51602-methylbutane78-78-45,0002-Propanol (IPA)67-63-05,000Acetone67-64-15,000Acetonitrile75-05-8410Benzene71-43-22Butane106-97-85,000Cumene98-82-870Cyclohexane110-82-73,880Dichloromethane75-09-26002,2-dimethylbutane75-83-22902,3-dimethylbutane79-29-82901,2-dimethylbenzene95-47-6See Xylenes1,3-dimethylbenzene108-38-3See Xylenes1,4-dimethylbenzene106-42-3See XylenesDimethyl sulfoxide67-68-55,000Ethanol64-17-55,000Ethyl acetate141-78-65,000

      Ethylbenzene100-41-4See XylenesEthyl ether60-29-75,000Ethylene glycol107-21-1620Ethylene Oxide75-21-850Heptane142-82-55,000n-Hexane110-54-3290Isopropyl acetate2905,000Methanol67-56-13,000Methylpropane75-28-55,0002-Methylpentane107-83-52903-Methylpentane96-14-0290N,N-dimethylacetamide127-19-51,090N,N-dimethylformamide68-12-2880Pentane109-66-05,000Propane74-98-65,000Pyridine110-86-1100Sulfolane126-33-0160Tetrahydrofuran109-99-9720Toluene108-88-3890Xylenes1330-20-72,170

2. (2) Xylenes is a combination of the following:

   1. (a) 1,2-dimethylbenzene;
   2. (b) 1,3-dimethylbenzene;
   3. (c) 1,4-dimethylbenzene; and
   4. (d) ethyl benzene.

KEY: industrial hemp, cannabinoid, testing

Date of Last Change: August 18, 2025

Authorizing, and Implemented or Interpreted Law: 4-41-204(2)