1. (a) A physician assistant who is recognized by the Board to prescribe under the direction of a delegating physician and is in compliance with the registration requirements of the Uniform Controlled Dangerous Substances Act, in good faith and in the course of professional practice only, may issue prescriptions, orders for home health pursuant to 63 O.S. §1-1961(4), and orders for medical supplies, services and drugs, including controlled medications in Schedules III, IV, and V pursuant to 63 O.S. §2-312 as delegated by the delegating physician and as approved in the Physician Assistant Drug Formulary (OAC 435:15-11-2).
2. (b) ­Any prescription for a pure form or combination of the following generic classes of drugs, listed in 435:15‑11‑2, may be prescribed unless the drug or class of drugs is listed as excluded. Written prescriptions for drugs or classes of drugs that are excluded may be transmitted, only with the direct order of the delegating physician.
3. (c) Prescriptions for non-controlled medications may be written for up to a 100-day supply with three (3) refills of a prescription.
4. (d) Prescriptions for Schedules III, IV and V controlled medications may be written for up to a 30-day supply. Up to two refills of the original prescription are allowed. Opioid prescriptions shall be written consistent with 63 O.S. Sec. 2-309(I). In order for a physician assistant to prescribe a controlled substance in an out-patient setting, the physician assistant must be currently registered with the Drug Enforcement Administration and Oklahoma Bureau of Narcotics and Dangerous Drugs.
5. (e) A physician assistant may write an order for a Schedule II drug for immediate or ongoing administration on site as defined in OAC 435:15-1-1.1. Prescriptions and orders for Schedule II drugs written by a physician assistant must be included on a written protocol determined by the delegating physician and approved by the medical staff committee of the facility or by direct verbal order of the delegating physician. In order for a physician assistant to prescribe and order a Schedule II controlled substance for immediate or ongoing administration on site, the physician assistant must be currently registered with the Drug Enforcement Administration and Oklahoma Bureau of Narcotics and Dangerous Drugs.
6. (f) A prescription issued by a physician assistant, whether written or oral, shall be the joint responsibility of the physician assistant and delegating physician. The delegating physician shall be responsible for the formulation and/or approval of all orders and protocols which allow the physician assistant to issue prescriptions. Questions concerning a prescription may be directed either to the delegating physician whose name shall appear on the prescription blank or to the physician assistant.
7. (g) Physician Assistants may not dispense drugs, but may request, receive and sign for professional samples and may distribute professional samples directly to patients in accordance with written policies established by the delegating physician.

Added at 10 Ok Reg 4377, eff 7-27-93 (emergency)

Added at 11 Ok Reg 2331, eff 5-26-94

Amended at 16 Ok Reg 378, eff 10-6-98 (emergency)

Amended at 16 Ok Reg 1214, eff 5-14-99

Amended at 16 Ok Reg 3595, eff 8-25-99 (emergency)

Amended at 17 Ok Reg 1352, eff 5-11-00

Amended at 19 Ok Reg 2303, eff 6-28-02

Amended at 24 Ok Reg 1102, eff 7-1-07

Amended at 26 Ok Reg 1079, eff 5-11-09

Amended at 33 Ok Reg 946, eff 8-26-16

Amended at 42 Ok Reg, Number 21, effective 7-25-25

<div>Amended at 43 Ok Reg, Number 1, effective 8-13-25 (emergency)</div>