N.Y. Comp. Codes R. & Regs. tit. 6, § 236.3
(a) Any owner or operator of a synthetic organic chemical manufacturing facility must monitor each of the following process unit components for leaks, on a quarterly schedule:
(c) Any owner or operator of a synthetic organic chemical manufacturing facility must also comply with the following component standards:
(3) Open-ended valves or lines in gas/vapor or light liquid service must be sealed with either a second valve, blind flange, cap, or plug. The sealing device may only be removed while a sample is being taken or during maintenance operations.