Specific deficiency - The ASCII .txt file purported to contain the computer readable form (CRF) copy of the "Sequence Listing" filed with this application in accordance with 37 CFR 1.821(c) has been found to be damaged, unreadable, or otherwise contains an error as indicated on document "Computer Readable Form (CRF) for Sequence Listing - Defective" dated.

Required response – Applicant must provide:

1. • a replacement "Sequence Listing" in the form of an ASCII plain text file under 37 CFR 1.821(c) as provided for in 37 CFR 1.825(b)(1)(i), together with
2. • An amendment specifically directing its entry into the application in accordance with 37 CFR 1.825(b)(3);
3. • A statement that the "Sequence Listing" includes no new matter as required by 37 CFR 1.825(b)(5); and
4. • A statement that indicates support for the amendment in the application, as filed, as required by 37 CFR 1.825(b)(4).
5. • A substitute specification in compliance with 37 CFR 1.52, 1.121(b)(3), and 1.125 inserting the required incorporation-by-reference paragraph, consisting of:
   1. • A copy of the previously-submitted specification, with deletions shown with strikethrough or brackets and insertions shown with underlining (marked-up version);
   2. • A copy of the amended specification without markings (clean version); and
   3. • A statement that the substitute specification contains no new matter;
6. OR
7. • A "Sequence Listing" part of the disclosure, as described above in item 1 c) or 1 d) as provided for in 37 CFR 1.825(b)(1)(ii) or 1.825(b)(1)(iii); together with
8. • An amendment specifically directing its entry into the application in accordance with 37 CFR 1.825(b)(2);
9. • A statement that the "Sequence Listing" includes no new matter as required by 37 CFR 1.825(b)(5); and
10. • A statement that indicates support for the amendment in the application, as filed, as required by 37 CFR 1.825(b)(4).
11. • When the "Sequence Listing" part of the disclosure is submitted according to item 1 c), or 1 d) above, Applicant must also provide:
    1. • A CRF in accordance with 37 CFR 1.821(e)(1) as required by 37 CFR 1.825(b)(6); and
    2. • a statement according to item 2) a) or b) above.

Examiner Note:

1. This form paragraph must be preceded by form paragraph 24.01.

2. This form paragraph should only be used for sequence listing non-compliance where a compliant sequence listing is not required for examination of the application.

3. This form paragraph should be used for an application where the CRF is damaged or unreadable, e.g., SCORE - CRF Problem Report.

4. This form paragraph may be followed by one or more deficiency form paragraphs.