105 C.M.R. 720.200
MASSACHUSETTS
LIST OF
INTERCHANGEABLE DRUGS
Department of Public Health regulation 105 CMR 720.050 describes the Massachusetts List of Interchangeable Drugs.
105 CMR 720.050(a) calls for the automatic adoption of all "A" rated drug products listed in the "Approved Drug Products with Therapeutic Equivalence Evaluations" and its supplements as published by the U.S. Food and Drug Administration (FDA), Department of Health and Human Services. This publication is commonly referred to as the "Orange Book". It is reprinted by the U.S. Pharmacopeial Convention Inc. (USP) as Volume III of the USP DI.
105 CMR 720.050(b) allows for the establishment of the Massachusetts Additional List of Interchangeable Drugs (Additional List), and provides the criteria upon which these drug products are approved.
All prescriptions written by generic name can be interchanged if the drug is multi-source. To determine if a prescription written for a brand name drug product is interchangeable in Massachusetts:
Copies of the "Approved Drug Products with Therapeutic Equivalence Evaluations" and its supplements ("Orange Book") are available from the:
U.S. Food and Drug Administration Department of Health and Human Services Government Printing Office Washington, D.C. 20402-9371 OPC 6768 (202) 783-3238 and www.fda.gov/cder/drug
Copies of the USP DI (third volume of USP DI is the "Orange Book") are available from:
The United States Pharmacopeial Convention, Inc., 12601 Twinbrook Parkway Rockville, MD 20852 (301) 881-0666
Copies of the Massachusetts Additional List of Interchangeable Drug Products (document number 105 CMR 720.000) are available from:
The State House Bookstore Room 116 Boston, MA 02133 (617) 727-2834 and www.magnet.state.ma.us/dph/dcp/Drug Formulary/Drug Interchange
TABLE OF CONTENTS
Foreword
Introduction
Drug Product Problem Reporting Instructions
Exception List
Format of the Additional List
NDA, ANDA, Applicant (name) Changes
Abbreviations
Massachusetts Additional List of Interchangeable Drugs (Alphabetical list of Official (Generic) Drug Names)
Partial Proprietary Brand Cross-reference
FOREWORD
The Massachusetts List of Interchangeable Drugs, is prepared by the Drug Formulary Commission (DFC) and the Department of Public Health. The DFC is comprised of nine men and women appointed by the Governor for the express purpose of developing a list of those drug products that are safely interchangeable -- that is, equivalent to each other in all significant respects. The DFC was established by M.G.L. c. 17, § 13. This law was enacted with the intent of saving money for consumers of prescription drugs, since drug products that are marketed under trademark or proprietary names are often available in the generic forms from competing manufacturers at substantially lower prices. M.G.L. c. 112, § 12D mandates prescription forms that allow practitioners to prescribe interchangeable drug products by simply signing the signature line. If a practitioner determines that a brand name drug product should be dispensed, he/she must sign the signature line and write the words "no substitution" in his/her own handwriting in the space provided below the signature line.
The regulations call for the automatic adoption of "A"rated drug products listed in the "Approved Drug Products with Therapeutic Equivalence Evaluations" and its supplements (commonly referred to as the "Orange Book") as published by the U.S. Food and Drug Administration, Department of Healthand Human Services, plus a list of additional drug products, the Massachusetts Additional List of Interchangeable Drugs ("Additional List"), individually reviewed and approved by the DFC and the Department. The regulations provide the criteria upon which the drug products listed on the Additional List are approved for interchange. The regulations also provide the DFC and the Department with the authority to review any "A" rated drug product listed in the "Orange Book" or drug product approved for interchange on the Additional List and delete it from the list of interchangeable drug products if deemed appropriate. Drug products assigned an "A" rating by FDA which are deleted from the Massachusetts List are placed on the Exception List. Drug products listed on the Additional List which are subsequently deleted are removed from the Additional List.
Of the many factors considered by the Commission in determining which drugs to include on the List, equivalent safety and effectiveness are paramount. The Commission reviews evidence on bioequivalence and pharmaceutical equivalence and includes on the List only those drug products determined to be fully interchangeable and whose manufacturers are approved by the U.S. Food and Drug Administration. Practitioners may prescribe any drug that appears on the List with confidence that it is as safe and effective as its brand name counterpart.
The efforts of the Commission in the assessment and evaluation of data and the preparation of the List are to be commended. The Department presents the Massachusetts List of Interchangeable Drugs with pride and with confidence that the List will greatly benefit consumers throughout the Commonwealth.
INTRODUCTION
INTERCHANGEABLE (GENERIC) DRUG LAW
In 1976 the Massachusetts Legislature passed an Act Further Regulating the Establishment of a Formulary of Interchangeable Drug Products (St. 1976, c. 470, § 13), commonly known as the Generic Drug Law. This law, enacted to promote and regulate the use of generic drugs, created the Drug Formulary Commission to develop a list of interchangeable drug products and also required the use of a standard prescription form to encourage practitioners to prescribe generic drugs.
PRESCRIPTION FORM
M.G.L. c. 112, § 12D mandates prescription forms with one signature line. If the prescriber signs the prescription form and writes the words "no substitution" in his/her own handwriting in the space provided below the signature line, the pharmacist must fill the prescription exactly as indicated, with no interchange permitted. However, if the prescriber signs the prescription and does not write "no substitution" under his/her signature, the pharmacist is legally required to dispense a less expensive, equivalent interchangeable drug product listed in the Massachusetts List of Interchangeable Drugs if one is reasonably available.
MASSACHUSETTS LIST OF INTERCHANGEABLE DRUGS
The Massachusetts List of Interchangeable Drugs (MLID) consists of the "A" rated drug products listed in the "Approved Drug Products with Therapeutic Equivalence Evaluations" and its supplements as published by the U.S. Food and Drug Administration, Department of Health and Human Services ("Orange Book") and the Massachusetts Additional List of Interchangeable Drugs (Additional List). The Additional List is developed by the Drug Formulary Commission. The Commission determines drug products to be interchangeable only when they meet certain criteria:
The Commission judges that all the drugs included on the MLID meet these standards and are bioequivalent, if essential, based on assessment and evaluation of the U.S. Pharmacopeia and its supplements, other state and hospital formularies, listings of the U.S. Department of Health and Human Services of the FDA, and on the expertise of its members.
The List does not include: (a) drugs that are protected by patent rights or available from only one source; (b) many controlled-release and enteric coated drug products since they may not consistently deliver the same quantities of their active ingredients; (c) those drugs for which the Commission had any significant doubt about safe interchange between manufacturers; and (d) any drug for which bioequivalence is considered essential but for which bioequivalence has not been demonstrated or an appropriate standard for bioequivalence has not been established.
Bioequivalence is determined to be necessary for a particular drug when bioinequivalence might result in therapeutic failure or hazard to the patient. Bioequivalent drug products do not show a significant difference in the rate and extent of absorption when administered at the same dosage under similar conditions. Drugs that are equivalent in the extent to which they are absorbed into a patient's body that differ in the rate of absorption may be therapeutically equivalent -- having the same medical effect -- either because the rate of absorption is not essential to the attainment of effective body concentrations of the drug, or because the difference in the rate is otherwise considered medically insignificant. Bioequivalence is a primary
consideration for those drug products with a narrow therapeutic/toxic dosage range (when variation in the rate or extentof absorption could have a critical effect) where careful determination of the correct dosage and monitoring ofthe patient is essential to safe and effective use. To determine for which drugs bioequivalence is essential, the Commission relies on expert medical testimony, studies done by the pharmaceutical industry, the knowledge and expertise of the individual members of the Commission, and advice from the FDA.
All drug products manufactured by FDA approved firms are considered safe and effective for their intended use, even if the product has not been included in the MLID. A practitioner may begin a patient's therapy with a drug product from any manufacturerwho has beenapproved by the FDA, even though interchange of the drug once the dosage has been calculated for the individual is not advised.
Several generic drug products are manufactured under the same new drug application (NDA) as the brand name drug products. According to section 1.6 of the Orange Book, drug products with the same NDA are therapeutically equivalent. Massachusetts regulations allow the interchange of these products. Distributors or repackagers of drug products manufactured under the same NDA as the brand name product are not identified in the Orange Book. Pharmacists who may not be able to determine if drug products are interchangeable should contact the manufacturers, distributors or repackagers. In addition the Department maintains an unofficial list of these products.
Information relative to the Interchangeable (Generic) Drug Law may be obtained from the Department of Public Health, Division of Food and Drugs, 305 South Street, Jamaica Plain, MA 02130, telephone number (617) 727-2670, and fromthe Boards ofRegistrationin Medicine, Dentistry and Pharmacy.
DRUG PRODUCT PROBLEM REPORTING INSTRUCTIONS
Since 1971 the United States Pharmacopeia (USP), in cooperation with various professional associations and the Food and Drug Administration (FDA), has operated the Drug Product Problem Reporting Program. This program can be utilized by pharmacists, physicians, or consumers to report any product problems encountered when using drugs interchanged under the Massachusetts generic drug law. The program is product oriented, and patient identification not requested. Should you prefer to remain anonymous, so indicate to the USP and your name will be withheld from the manufacturer and the FDA. Your participation in reporting problems will help to ensure that the drug products prescribed and dispensed in Massachusetts are of continued high quality.
Reports should be sent to The United States Pharmacopeial Convention, Inc., 12601 Twinbrook Parkway, Rockville, MD 20852, (301) 881-0666. The USP is an impartial, non-governmental organization concerned with drug standards and quality control. After USP receives a report, copies are forwarded to the FDA and to the manufacturer of the product involved. Either the FDA or the manufacturer may act to investigate or correct problems.
EXCEPTION LIST
Orange Book "A" rated drug products not approved for interchange.
There are currently no products designated to be listed on the Exception List.
ADDITIONAL LIST
The Massachusetts Additional List of Interchangeable Drugs (Additional List) has been printed in a format designed to be concise and understandable. Interchangeable drugs are listed alphabetically according to their official (chemical or generic) names, and separate sections in each listing show dosage forms, strengths, FDA approved manufacturers, and categories.
DRUG
Drugs are listed in alphabetical order by their generic names and are printed in capital letters. Drug products containing more than one active ingredient (for example, CODEINE PHOSPHATE, GUAIFENESIN) are listed in the conventional order of ingredients.
Only drug products grouped under single headings are to be interchanged.
DOSAGE FORM
Under the generic names are listed the various multisource dosage forms in which a drug product is available. Abbreviations used for dosage forms and approved manufacturers are found in the front of the Additional List.
Only identical dosage forms and strengths of identical drugs are to be interchanged.
STRENGTH
The approved strengths of the drug products are listed under the heading "Strength(s)." The "strengths" must be read along with the "dosage forms" since any strength shown is available only for the dosage form directly to its left. Dosage strength is in metric units that are sometimes rounded off from apothecary measures, which may introduce slight variations in the strength of certain products. Single ingredient drug product strengths are separated by commas. Combination drug products have a slash separating the strengths of the individual ingredients. If more than one strength of a single component of a combination drug product is approved, they will be separated by commas. For example, the strength of a tablet of aspirin with codeine phosphate is "325mg / 15mg, 30mg, 60mg" which means that the combination is available with 325 milligrams of aspirin and 15, 30, or 60 milligrams of codeine phosphate. Drug products with three or more components have their active ingredients listed individually in parentheses and have slashes separating the strengths of the individual ingredients.
MANUFACTURERS
Next to the heading "Manufacturers" are all approved manufacturers for the drug product in that group, listed by three letter abbreviations in capital letters. (See list of manufacturer abbreviations in front of the Additional List.) Listed manufacturers have met all legal requirements, including compliance with the FDA Good Manufacturing Practices for the production of the drug product indicated. Approved manufacturers hold current new drug applications (NDAs) or abbreviated new drug applications (ANDAs) when required by law.
NDA, ANDA APPLICANT (NAME) CHANGES
Because it is not practical to identify in the Massachusetts Additional List of Interchangeable Drugs (Additional List) each and every product involved when an applicant transfers its entire line of approved drug products to another applicant, or when an applicant changes its name, these transfers and name changes are identified in this section. In addition, the new manufacturers are listed in parenthesis beside the original manufacturer under the Manufacturers' Abbreviations section of the Additional List. Where only partial approved product lines are transferred between applicants, each approved product involved will appear with the manufacturer name change in the Additional List amendment.
Previously listed name changes have been incorporated into the revised Manufacturers’ Abbreviations section.
ABBREVIATIONS
The following abbreviations are used in the Massachusetts List of Interchangeable Drugs.
DOSAGE FORMS
aero aerosol ml milliliter amp ampule oint ointment cap capsule ophth ophthalmic conc concentrate oral gran oral granules for e.c. enteric-coated reconstitution elix elixir oral powder oral powder for g gram reconstitution Hbr hydrobromide oral sol oral solution HCl hydrochloride pow powder HC hydrocortisone sol solution inhl inhalation SR sustained release inhl liquid inhalation liquid subl tab sublingual tablet inhl sol inhalation solution supp suppository inj injection susp suspension irr sol irrigating solution syr syrup I.U. international units tab tablet liq liquid top aero topical aerosol lot lotion top swab topical swab mcg microgram U units mEq milliequivalents vag vaginal mg milligram
MANUFACTURERS' ABBREVIATIONS
3MP 3M Pharmaceutical Inc AAA Alpha Therapeutic ARC Arcola Labs. ABB Abbott APC Arcum Pharmaceuticlal Corp. ABI Abic ARP Armenpharm ABL Able Laboratories ARM Armour Pharmaceuticals ACI ACIC Limited ASC Ascot Hospital Products ACP Advanced Care Prod. ASA Asta ADV Advanced Remedies ASP Astra Pharmaceuticals LP AGV Agvar Chemicals ATH Athena Neurosciences AKO Akorn BAK Baker Norton AKZ Akzona Inc. BAN Banner Pharmacaps ALC Alcon Labs BAP Barlan Pharmacal ALL Allergan Pharmaceuticals B/I Boehringer Ingelheim ALI Alliance Pharmaceutical B/M Boehringer Mannheim. Ther. Div ALP Alpharma BAR Barr Labs APP Alphapharm Party BAS Basel Pharmaceuticals ALT Altana BAT Bartor ALZ Alza Corp. B&L Bausch & Lomb ALR Alra Laboratories BAY Bayer Corp AMA Amaric BEA Beach Prod. AMB Ambix Labs B-D Becton,Dickinson & Co. ACC American Cyanamid Co. BED Bedford Laboratories AHP American Home Products BEL Bell ARL American Regent Labs. BDP Beta Derm Pharmaceuticals AME Amersham BER Berlex AMG Amgen BFA B.F. Asher AMI Amide Pharmaceuticals BHC B.H. Chemicals AMT American Therapeutics BID Biodevelopment ANA Anabolic BIO Bio Technology General ANB Anbex BIV Biovail ANC Angus Chemical BLA Blairex Laboratories ANE Anesta BLO Block Drug Co. ANG Angelini APO Apothecon APK Apothekernes APP American Pharmaceutical Partners
BLU Bluline DIS Dista BRL Blue Ridge Laboratories DMD Duramed BOC Bock Pharmacal DMG D M Graham Laboratories BOW Bowman Pharm. DOW Dow Pharmaceutical BMS Bristol Myers Squibb DPT Dupont Pharmaceuticals BRC Bracco Diagnostics DPM Dupont Merck BRD Bradley Pharm. DUR Dura Pharmaceuticals BRA Braintree Laboratories DUN Dunhall BRI Bristol-Myers Prod. DYN Dynapharm BTG BTG Pharmaceuticals E/K Eastman Kodak BVL Ben-Venue Labs EAT Eaton Medical Corp. BYR Byron Chemical ECR ECR Pharmaceuticals C&M C & M Pharmacal ELA Elan Pharmaceuticals CAD Cadema Medical Products ELL Ellis Pharmaceuticals CAG Calgon Corp. EMP EM Pharma CDC Carderm Capital END Endo C-P Chesebrough - Ponds EON Eon Laboratories C-W Cook - Waite ENQ Enquay Pharm C/C Chase Chemical ENZ Enzon CSL Chase Laboratories ESR Elkins-Sinn/AH Robins C/P Corvit Pharmaceuticals ERS Ersana CAL Carlisle ESI ESI Lederle Generics CAM Camall ESP ESI Pharmacal CAR Carnick Labs ETH Ethicon Inc. CTW CarterWallace ETX Ethex CEN Century Pharmaceuticals ETK Ethitek Pharmaceuticals CBV Cetus Ben Venue Therapeutics EVY Everylife CHA Chamberlin Parenteral Corp. EZC E Z EM Co. CHE Chelsea Laboratories FAU Faulding Pharm. Co. CHM Chemed Corp. FER Ferndale CVO Ciba Vision Ophthalmics FRT Ferrante CIR Circa Pharmaceuticals FRR Ferring Labs CJD Copanos, J.D. FIS Fisons CLA Clay - Park FLE Fleming & Co. CLO Clonmel Healthcare FOR Forest CMB C.M. Bundy FOU Fougera CMC Consolidated Midland Corp. FOY Foy C/T Controlled Therapeutics FRE Fresenius CMP Carolina Medical Products G&W G & W CNC H.R. Cenci GAL Galderma COL Colgate Palmolive GEI Geigy COM Combe GEC Gencon CON Connaught Laboratories GED Genderm COO Cooper Labs GET Genentech COP Copley Pharmaceutical GEP Genpharm CPG Consolidated Pharmacy Group GEV Geneva CRE Creighton Products GES Gensia Sicor Pharmaceuticals Inc CUM Cumberland Swan GEZ Genzyme CUR Curatex Pharmaceuticals GIL Gilbert Laboratories CTL Central Pharmacal GLD Glades D&G Davis & Geck GLW GlaxoWellcome D/L DPT Laboratories GLE Glenwood D-R Del-Ray Laboratories Inc. GLO Global Pharm. DAN Danbury Pharmacal G/P Golden Pharms. DAR Darby Group Companies GOL Goldine DEL Dell GRE Greenstone DEP Deproco GRI Griffen,KW DER Dermik Laboratories G/L Gruppo Lepetit DES Deseret Medical GUA Guardian DEY Deylabs GYM GYMA Laboratories DHL DHL Laboratories GYN Gynopharm DIA Dial Corp. H-R Holland-Rantos
HAL Halsey Labs LEO Leo Pharms HAM Hamilton Pharmaceuticals LIF Life Labs HAN Hnford GC LIL Lilly HEA Heather LIP Liposome HEN Heran Pharmaceutical LIQ Liquipharm HEX Hexcel Chemical Products LNK LNK International HER Hermal Pharmaceutical LOC Loch Pharmaceuticals HIC Hickam LOR Lorex H/D Hill Dermaceuticals LOT Lotus Biochemical HIR Hirsch Industries LPI LPI Holding HIT Hi Tech Pharma LUI Luitpold HTP High Technology Pharmacal LUS Lek USA Inc. HLC Halocarbon LYN LYNE Laboratories HCC Hoechst Celanese Corp. M/P Mallinckrodt Pharmaceutical. HMR Hoechst Marion Roussell MAY Mayrand HOE Hoechst-Rousel MAT Matrix Labs HOR Horus Therapeutics MCG Mcgaw HOY Hoyt MCN McNeil Consumer Products HUD Hudson Pharmaceuticals MDP MD Pharmaceuticals HUN Huntington MEA Mead Johnson HYB Hybritec Inc. MJN Mead Johnson Nutritionals HYG Hygenics M/R Medco Research HYR Hyrex MVA Medeva IMM Immunex MEP Medics Pharmaceuticals IMP IMP Inc. MPI Medi Physics, Inc. ICN ICN Pharmaceuticals MAG Mepha AG IMS International Medication MER Mericon INP Interpharm MET Metronic INV Invamed, Inc. MGI MGI Pharma INW Inwood Labs MID Midway Medical ICC Interchem Corp. MIK Mikart Laboratories ILC International Latex Corp. MIS Mission Pharmacol ING Ingram Pharmaceutical MJP MJ Pharmaceuticals INH Inhalon MKL Moore Kirk Labs IOL Iolab MLI Marchar Laboratories IOM Iomed MLP Miller Pharmacal IPR IPR Pharm MLX Milex IVA IVAX MMD Marion Merrell Dow J&J Johnson & Johnson MOR Morton Grove JAC Jacobus MCK Merck & Co. JAN Janssen Pharmaceuticals MSM Marsam JER Jerome Stevens Labs MSL Marshall Pharmacal JRW Johnson RW MTC Martec JON Jones Pharma Inc MOV Mova KAL Kalapharm MUR Muro KBP Kabi Pharmacia MUT Mutual Pharmaceuticals KEE Keene MYL Mylan Pharmaceuticals KED Kendall NEP Nephron Pharmaceuticals Inc KEN Kenwood NEU Neutrogena KIN King Pharmaceuticals NOR Norbrook Laboratories KIR Kirkman Sales N/W Norton Waterford KNO Knoll N/N Novo Nordisk KPI Key Pharmaceuticals NEW Newtron Pharmaceuticals KVP KV Pharmaceutical Co. NHN Norton HN L/F Labs Fournier NOV Novocol L/A Laboratories Atral NVP Novopharm Ltd. LAF Lafayette Pharms NUM Numark LAN Lannett NYC Nycomed LED Lederle NYL Nylos Trading LEI Leiras ORI Organon, Inc. LEK Lek Ljubliana OCL Oclassen LEM Lemmon OHM OHM Laboratories
OMD Ohmeda Pharmaceutical RBP Roberts Pharmaceutical OSA On Site Azla ROR Rorer ODC Ormont Drug & Chemical ROS Ross Labs OPC Ortho Pharmaceuticals ROX Roxane Labs OPT Optopic Laboratories Corp. ROY Royce Laboratories ORG Organics RPC Rosemont Pharmaceutical Corp. OAP Otsuka America Pharmaceutical RUG Rugby Labs PAK Pal-Pak S-M Spencer-Mead PAL Palisades S/W Sanofi Winthrop P/D Parke Davis S/L Schmid Laboratories P/I Plantex/Ikpharm SAK Sankyo P/K Purepac-Kalipharma SAV Savage Labs/Altana P/P Parmed Pharmaceuticals SAN Sandoz PAC Paco Research SCE Scherer, R.P. PAD Paddock Labs SPI Schein Pharmaceutical, Inc. PHD Pharmaderm SCH Schering Corporation PAN Panray S/P Schering/Plough PAR Par SWZ Schwarz Pharma PNL Parnell SZG SchwarzGMBH PER Perrigo SCI ScinoPharm International PCE Pharmachemie SCS SCS Pharmaceuticals PHC Pharmics SEA Searle PHK Pharmakinetics Labs SER Serono Laboratories PHM Pharmeral SEQ Sequus Pharmaceuticals PHO Phoenix Labs SHM Sherwood Medical PHS Pharma Serve SHI Shionogi USA PHT Pharmaton SID Sidmak Laboratories PFF Pfeiffer SIG Sigma Tau PFI Pfizer SIX Silarx P/U Pharmacia & Upjohn SKB Smith, Kline Beecham P/A Pharmaceutical Association SBH Sola Barnes Hind PIO Pioneer Pharmaceutical Inc. SOL Solopak Laboratories PPI Physicians Products Inc. SLV Solvay PSA Pharmaceutical Specialist Assoc SOM Somerset POH Pohl Boskamp SBM Sorin Biomedics POL Polymedia SDP Sperti Drug Products PGP Prographarm STI Steifel PRD Professional Disposables STL Stanlabs Pharmaceutical Co. PRO Proter Laboratory STR Star Pharmaceuticals PRI Private Formulations STS Steris Laboratories P&G Proctor & Gamble STZ Storz Ophthalmics PRV Pharmavite SUP Superpharm PTK Pharma-Tek SPP Suppositoria PUF Purdue Frederick SUR Survival Technology PUR Purepac SYN Syntex QUA Quantum Pharmics Ltd. SYO Syosset Labs QLT QLT PhototherapeuticsInc. TAB Tablicaps RAN Ranbaxy Pharmaceuticals TAG Tag Pharmaceuticals R/C Reckitt & Colman TAK Takeda R&C Reed & Carnrick TAP Tap Holdings R/I Research Industries TAR Taro Pharmaceutical RXP Rexar Pharmacal TAY Taylor Pharmaceuticals RAC Rachelle Labs TEC Technilab REN Ren-Pharm Internatl. Ltd. THE Theratech RHP Rhone - Poulenc THK Therakos RPR Rhone-Poulenc Rorer THA Thames Phamacol Co. Inc. RAH Robins, A.H. TIC Tican Pharmaceuticals REX Rexall/Sundown TOP Topiderm RIC Richlyn Labs T/L Torch Laboratories ROC Roche Labs. TOR Torigian Lab RPF Roerig/Pfizer UDL UDL Laboratories ROA Roaco UMD Unimed
UPJ Upjohn WPP West Point Pharma USL Upsher-Smith Labs WES Westwood Squibb Pharmaceuticals VAL Vale Chemical W-W West-Ward VAN Vangard W/L Wharton Labs VES Vestal WBY Whitby VIC Vicks Pharmacy Products WWT Whiteworth Towne VIN Vintage WAL Wallace Labs VIR Viratek WAR Warner-Lambert VIS Vistakon, Inc. WAT Watson Laboratories VIV Vivan Pharmacal WOC Wockhardt W-A Wyeth Ayerst XTT Xttrium Laboratories W-C Warner-Chilcott YAM Yamanouchi WAW Warner Wellcome YOS Yoshitomi Laboratories WRR Warrick Pharm ZCA Zeneca WEP WE Pharmaceuticals ZGP Zenith Goldline Pharmaceuticals WEN Wendt Laboratories
MASSACHUSETTS ADDITIONAL LIST OF INTERCHANGEABLE DRUGS
AM INOPHYLLINE, EPHEDRINE Hcl
Dosage form(s): TABLETS Strength(s): 130mg/25mg M anufacturers: STL Category: OTC
AM YL NITRITE
Dosage form(s): INHALATION Strength(s): 0.3ml M anufacturers: GLW, CM C Category: PRE-38
ASPIRIN W/ CODEINE PHOSPHATE
Dosage form(s): TABLET Strength(s): 325mg/15mg, 30mg, 60mg M anufacturers: BAR, GLW, CHE, GEV, HAL, P/D, ZGP Category: PRE-38
ATROPINE SULFATE
Dosage form(s): OPHTHALM IC SOLUTION Strength(s): 0.5%, 1%, 2%
OPHTHALM IC OINTM ENT 0.5%, 1%
M anufacturers: ALC, ALL, ESR, FOU, INV, M UR, B&L, STS, SUR Category: PRE-38
ATROPINE SULFATE COM POUND (ATROPINE SULFATE, SCOPOLAM INE HBr, HYOSCYAM INE SULFATE, PHENOBARBITAL)
Dosage form(s): TABLET Strength(s): 0.0194mg/0.0065mg/
0 1037mg/16.2mg
M anufacturers: ALL, CHE, M /P, M AY, TAY, RAH, WES Category: DESI
BENZOCAINE, ANTIPYRINE
Dosage form(s): OTIC SOLUTION Strength(s): 1.4%, 5.4% M anufacturers: AM B, W-A, CLA, RPC, S-M , THA Category: PRE-38
BENZOYL PEROXIDE
Dosage form(s): GELStrength(s): 2.5%, 5%, 10% M anufacturers: BM S, CLA, GAL, STI, SYO, VIC, WES Category: OTC
BENZTHIAZIDE
Dosage form(s): TABLET Strength(s): 50mg M anufacturers: GEV, PFI, RAH, Category: B
BROM PHENIRAM INE M ALEATE, DEXTROM ETHORPHAN HBr, PSEUDOEPHEDRINE HCl
Dosage form(s): SYRUP Strength(s): 2mg/10mg/30mg/5ml M anufacturers: RAH, RPC Category: OTC
MASSACHUSETTS ADDITIONAL LIST OF INTERCHANGEABLE DRUGS
BROM PHENIRAM INE M ALEATE, PHENYLPROPANOLAM INE HCl, PHENYLEPHRINE, GUAIFENESIN COM BINATION
Dosage form(s): SYRUP Strength(s): 4mg/5mg/5mg/100mg/5ml M anufacturers: HAL, LIF, RAH, RPC, Category: OTC
CAFFEINE AND SODIUM BENZOATE
Dosage form(s): INJECTION Strength(s): 250mg/ml M anufacturers: TAY Category: PRE-38
CALCIUM GLUCONATE
Dosage form(s): INJECTION Strength(s): 10% M anufacturers: ARL, APC, APP, CM C, CEN, BAY, ESR, GEN, HYR, KIR, LAN,
LIL, M /P, P/D, RIC, STL, P/U ,
Category: PRE-38
CARBINOXAM INE M ALEATE, PSEUDOEPHEDRINE HCl, DEXTROM ETHORPHAN HBr
Dosage form(s): DROPS Strength(s): 2mg/25mg/4mg/ml
SYRUP 4mg/60mg/15mg/5ml
M anufacturers: ALP, ROS Category: PRE-38
CHLORAL HYDRATE
Dosage form(s): CAPSULE Strength(s): 500mg
SYRUP 250mg/5ml, 500mg/5ml
M anufacturers: BM S, C/C, ALP, PHC, PUR, ROX, SCE, , ZEN Category: PRE-38
CHLORDIAZEPOXIDE W/ CLIDINIUM BROM IDE
Dosage form(s): CAPSULE Strength(s): 5mg/2.5mg M anufacturers: BAR, CHE, EON, GEV, HAL, ROC, LEM , PAR, QUA, ZGP Category: DESI
CHLOROTHIAZIDE W/ RESERPINE
Dosage form(s): TABLET Strength(s): 250mg/0.125mg, 500mg/0.125mg M anufacturers: M CK, M YL, Category: B
CHLORPHENIRAM INE M ALEATE
Dosage form(s): TABLET Strength(s): 4mg, 8mg, 12mg
SYRUP 2mg/5ml
M anufacturers: LAN, SCH Category: OTC
CHOLINE M AGNESIUM TRISALICYLATE (CHOLINE SALICYLATE, M AGNESIUM SALICYLATE)
Dosage form(s): TABLET Strength(s): 500mg (=293mg/362mg),
750mg (=440mg/544mg), 1000mg (=587mg/725mg)
M anufacturers: PUF, SID Category: PRE-38
CODEINE PHOSPHATE
Dosage form(s): INJECTION Strength(s): 15mg, 30mg, 60mg/ml M anufacturers: ESR, KNO, STL, W-A Category: PRE-38
CODEINE PHOSPHATE /GUAIFENESIN LIQUID
Dosage form(s): LIQUID Strength(s): 10mg/100mg/5ml M anufacturers: RAH, HAL Category: PRE-38
CYANOCOBALAM IN
Dosage form(s): TABLET Strength(s): 10mcg, 25mcg,
CAPSULE 50mcg, 100mcg, 250mcg
M anufacturers: APP, BER, BM S, STS, DEL, ESR, INV, LEM , LIL, M M D, M CK, ALP, ORI, P/D,
SAV, SOL, P/U, W-A
Category: OTC
MASSACHUSETTS ADDITIONAL LIST OF INTERCHANGEABLE DRUGS
CYCLANDELATE
Dosage form(s): CAPSULE Strength(s): 200mg/400mg M anufacturers: CHE, GEV, DAN, FOR, INW, W-A, LAN, LEM , M DP, PAR, PIO, ZGP Category: DESI
DEXAM ETHASONE
Dosage form(s): TABLET Strength(s):0.25mg, 0.5mg, 0.75mg, 1.5mg, 4mg M anufacturers: GEV, DAN, M CK, M YL, ORI, PAR, PRI, RIC, SLV, ROX, , USL Category: B
DIETHYLPROPION HCl
Dosage form(s): TABLET Strength(s): 25mg
SUSTAINED RELEASE TABLET 75mg
M anufacturers: CAM , , LEM , M M D, M DP, 3M P Category: B
DIETHYLSTILBESTROL
Dosage form(s): TABLET Strength(s): 0.1mg, 0.5mg, 1.5mg
VAGINAL SUPPOSITORIES
M anufacturers: BM S, LIL Category: B
DIGOXIN
Dosage form(s): TABLET Strength(s): 0.125mg, 0.25mg, 0.5 mg M anufacturers: GLW, AM I Category: PRE-38
DIGOXIN
Dosage form(s): INJECTION Strength(s): 0.25mg/ml, 0.5mg/2ml M anufacturers: GLW, ESR, EON, W-A Category: PRE-38
DIM ENHYDRINATE
Dosage form(s): TABLET Strength(s): 50mg M anufacturers: ANA, STS, CHE, GEV, ESR, LEM , SEA, , W-A Category: OTC
DIPHENHYDRAM INE HCl
Dosage form(s): CAPSULE Strength(s): 25mg, 50mg
ELIXIR 12.5mg/5ml
M anufacturers: HAL, ICN, P/D Category: OTC
DISULFIRAM
Dosage form(s): TABLET Strength(s): 250mg, 500mg M anufacturers: W-A, DAN Category: B
EPINEPHRINE HCl
Dosage form(s): INJECTION Strength(s): 0.01%, 0.1%
OPHTHALM IC SOLUTION 0.1%, 0.25%, 0.5%, 1%, 2%
M anufacturers: ABB, ALC, ALL, ARL, ESR,IM S, INV, LAN, P/D, W-A Category: PRE-38
ESTROGENS, ESTERIFIED
Dosage form(s): TABLET Strength(s): 0.3mg, 0.625mg, 1.25mg, 2.5mg M anufacturers: BM S, PRI, SLV, SKB, SYN Category: B
ETHAVERINE HCl
Dosage form(s): CAPSULE Strength(s): 100mg
TABLET
M anufacturers: BFA, KEN, LEM , M EP Category: PRE-38
ETHINYL ESTRADIOL
Dosage form(s): TABLET Strength(s): 0.02mg, 0.05mg M anufacturers: ORI, SCH, P/U Category: B
MASSACHUSETTS ADDITIONAL LIST OF INTERCHANGEABLE DRUGS
FLUOXYM ESTERONE
Dosage form(s): TABLET Strength(s): 2mg, 5mg, 10mg M anufacturers: BM S, RPC, P/U Category: B
GLYBURIDE
Dosage form(s): TABLET Strength(s): 1.25mg, 2.5mg, 5mg M anufacturers: HOE, P/U Category: B
HYDRALAZINE HCl, HYDROCHLOROTHIAZIDE, RESERPINE
Dosage form(s): TABLET Strength(s): 25mg/15mg/0.1mg M anufacturers: DAN, GEI, LEM Category: B
HYDROCHLOROTHIAZIDE W/ RESERPINE
Dosage form(s): TABLET Strength(s): 25mg/0.125mg, 50mg/0.125mg,
25mg/0.1mg, 50mg/0.1mg
M anufacturers: KNO, CAM , GEI, GEV, DAN, LEM , M CK, PUR, ZGP Category: B
HYDROCODONE BITARTRATE W/ PHENYLPROPANOLAM INE
Dosage form(s): SYRUP Strength(s): 5mg/25mg/5ml M anufacturers: DPT, ALP, RPC Category: OTHER
HYDROCORTISONE, IODOCHLORHYDROXYQUIN
Dosage form(s): CREAM Strength(s): 0.5%, 1% / 3%
OINTM ENT
M anufacturers: AM B, ALT, CLA, DER, BAY, DUR, GEI, LEM , ALP, SLV, THA, Category: DESI
HYDROFLUM ETHIAZIDE, RESERPINE
Dosage form(s): TABLET Strength(s): 25mg, 50mg/0.125mg M anufacturers: APO, RPC, ZGP Category: B
HYDROQUINONE 4% CREAM
Dosage form(s): TOPICAL CREAM Strength(s): 4% M anufacturers: ICN, ETX Category: PRE-62
HYDROQUINONE CREAM 4%
Dosage form(s): CREAM Strength(s): 4% M anufacturers: ICN; GLD Category: PRE-1962
HYDROQUINONE 4% CREAM with SUNCREENS
Dosage form(s): TOPICAL CREAM Strength(s): 4% M anufacturers: ICN, ETX Category: PRE-62
HYDROQUINONE CREAM 4% with SUNCREEN
Dosage form(s): CREAM Strength(s): 4% M anufacturers: ICN; GLD Category: PRE-1962
HYDROQUINONE TOPICAL SOLUTION
Dosage form(s): TOPICAL SOLUTION Strength(s): 3% M anufacturers: NEU, GLD Category: PRE-38
NON-TEXT PAGE
MASSACHUSETTS ADDITIONAL LIST OF INTERCHANGEABLE DRUGS
ISOSORBIDE DINITRATE
Dosage form(s): SUSTAINED RELEASE CAPSULE Strength(s): 40mg M anufacturers: ASC, GEV, FOR, W-A, SUP Category: B
ISOXSUPRINE HCl
Dosage form(s): TABLET Strength(s): 10mg, 20mg M anufacturers: GEV, M EA Category: PRE-38
L-HYOSCYAM INE SULFATE
Dosage form(s): TABLET Strength(s): 0.125mg M anufacturers: BFA, GLW, SWZ Category: PRE-38
LEVODOPA
Dosage form(s): TABLET Strength(s): 250mg, 500mg
CAPSULE 100, 250, 500mg
M anufacturers: ROC, P&G Category: B
M AGNESIUM SALICYLATE
Dosage form(s): TABLET Strength(s): 600mg M anufacturers: BFA, END, RBP, M LP, , Category: OTHER
M AGNESIUM SULFATE
Dosage form(s): INJECTION Strength(s): 10%, 12.5%, 50% M anufacturers: ABB, APP, ARL, CM C, ESR, IM S, LIL Category: PRE-38
M AZINDOL
Dosage form(s): TABLET Strength(s): 1mg M anufacturers: SAN, W-A Category: B
M EPHOBARBITAL
Dosage form(s): TABLET Strength(s): 32mg, 100mg, 200mg M anufacturers: BOW, ICN, S/W Category: PRE-38
M ETHENAM INE M ANDELATE
Dosage form(s): SUSPENSION Strength(s): 0.25, 0.5g/5ml
TABLET 0.25g, 0.5g, 1g ENTERIC COATED TABLET 0.25g, 0.5g, 1g
M anufacturers: GEV, HEA, ALP, P/D, RIC, SLV, TAB Category: PRE-38
M ETHENAM INE COM BINATION (M ETHENAM INE, PHENYLSALICYLATE, ATROPINE SULFATE, HYOSCYAM INE, BENZOIC ACID, M ETHYLENE BLUE)
Dosage form(s): TABLET Strength(s): 40.8mg/18mg/0.03mg/
0.03mg/4.5mg/5.4mg
M anufacturers: CHE, LEM , , S-M , STR Category: DESI
M ETHYLENE BLUE
Dosage form(s): INJECTION Strength(s): 1%
TABLET
M anufacturers: ARL, CM C, ESR, TAY, Category: PRE-38
MASSACHUSETTS ADDITIONAL LIST OF INTERCHANGEABLE DRUGS
M ETHYLTESTOSTERONE
Dosage form(s): CAPSULE Strength(s): 10mg
SUBL. TABLET 10mg, 25mg
M anufacturers: DAN, INW, LAN, PUR, SCH Category: B
M ORPHINE SULFATE
Dosage form(s): SUSTAINED RELEASE TABLET Strength(s): 30mg, 60mg, 100mg M anufacturers: PUF, ROX Category: B
NEOSTIGM INE M ETHYLSULFATE
Dosage form(s): INJECTION Strength(s): 1-1000, 1-2000, 1-4000 M anufacturers: CM C, ESR, LAN, S-M , Category: PRE-38
NITROGLYCERIN
Dosage form(s): SUBLINGUAL TABLET Strength(s): 0.3mg, 0.4mg, 0.6mg M anufacturers: P/D ETX Category: PRE-38
NORTRIPTYLINE HCl
Dosage form(s): CAPSULE Strength(s): 10mg, 25mg M anufacturers: LIL, SAN Category: B
NYLIDRIN
Dosage form(s): TABLET Strength(s): 6mg, 12mg M anufacturers: GEV, C/P, DAN, ROR, ZGP Category: DESI
OPIUM TINCTURE, DEODORIZED
Dosage form(s): LIQUID Strength(s): 10% OPIUM M anufacturers: HAL, LIL Category: PRE-38
PAPAVERINE HCl (NON-SUSTAINED RELEASE)
Dosage form(s): INJECTION Strength(s): 30mg/ml
CAPSULE 75mg, 150mg, 300mg TABLET 30mg, 60mg, 100mg, 150mg, 200mg, 300mg
M anufacturers: CHE, CM C, GEV, DAN, HAL, HEA, LAN, LEM , M M D, M YL, PUR, REN, SLV, VAN,
EON, ZGP
Category: PRE-38
PARALDEHYDE
Dosage form(s): LIQUID Strength(s): 100%
INJECTION
M anufacturers: CM C, ESR, Category: PRE-38
PAREGORIC
Dosage form(s): LIQUID Strength(s): 2mg M ORPHINE EQUIV./5ml M anufacturers: APC, BOW, HAL, LAN, LIL, ALP, P/D, PUR, ROX, RPC, STL Category: OTC
PENICILLIN G BENZATHINE
Dosage form(s): INJECTION Strength(s): 600, 000 UNITS/ml M anufacturers: PFI, W-A Category: B
PENTAERYTHRITOL TETRANITRATE
Dosage form(s): TABLET Strength(s): 10, 20
SUSTAINED ACTION TABLET 80mg
M anufacturers: COO, GEV, DAN, INW, KIR, M ER, P/D, PUR, STA, S-M , ZGP Category: DESI
MASSACHUSETTS ADDITIONAL LIST OF INTERCHANGEABLE DRUGS
PHENAZOPYRIDINE HCl
Dosage form(s): TABLET Strength(s): 100mg, 200mg M anufacturers: AM I, BAR, COP, C-P, LAN, P/D, QUA, RIC, S-M , TAB, VAN, Category: PRE-38
PHENOBARBITAL
Dosage form(s): ELIXIR Strength(s): 20mg/5ml
TABLET 15mg, 16mg, 30mg, 32mg, 60mg, 65mg, 100mg
M anufacturers: APC, BAR, BOW, GEV, C/P, DAN, HAL, ICN, INW, LAN, LED, LEM , LIL, M M D, ALP,
P/D, PUR, REX, ROX, RUG, STL, STA, TAB, EON, W-W, S/W, W-A, ZGP
Category: PRE-38
PHENYLEPHRINE HCl
Dosage form(s): SOLUTION Strength(s): 0.25%, 1%
OPHTHALM IC SOLUTION 0.12, 2.5, 10%
M anufacturers: AKO, ALC, ALL, ALP, M UR, B&L, PUF, RPC, STS, S/W Category: PRE-38
PHENYLPROPANOLAM INE HCl, PHENYLEPHRINE HCl, PHENYLTOLOXAM INE CITRATE, CHLORPHENIRAM INE M ALEATE
Dosage form(s): PEDIATRIC DROPS Strength(s): 5mg/1.25mg/2mg/0.5mg/ml
PEDIATRIC SYRUP 5mg/1.25mg/2mg/0.5mg/5ml
M anufacturers: ALP, APO Category: PRE-38
PHYTONADIONE
Dosage form(s): INJECTION Strength(s): 2mg, 10mg/ml M anufacturers: ABB, ROC, IM S, M CK, SKB Category: B
PILOCARPINE HCl
Dosage form(s): OPHTHALM IC SOLUTION Strength(s): 0.25%, 0.5%, 1%, 2%, 3%, 4%, 6%,
8%
M anufacturers: ALC, CVO, W-A, OPT, B&L, PRO, STS Category: PRE-38
PIPERAZINE CITRATE
Dosage form(s): SYRUP Strength(s): 500mg/5ml
TABLET 250mg, 500mg
M anufacturers: BLU,ALP, GLW, LAN, SLV, S/W Category: PRE-38
POTASSIUM GLUCONATE
Dosage form(s): LIQUID Strength(s): 20mEq/15ml M anufacturers: ALP, CM C, GEV, LAN, LED, , RAH, ROX, RPC, S-M , Category: B
POTASSIUM IODIDE
Dosage form(s): LIQUID Strength(s): SATURATED SOLUTION M anufacturers: ALP, CM C, GEN, GEV, P/R, ROX, RPC, STL, , USL Category: PRE-38
PREDNISOLONE ACETATE
Dosage form(s): INJECTION Strength(s): 25, 50, 100mg/ml M anufacturers: ALC, ALL, CTL, STS, LEM , B&L, SCH Category: B
PREDNISOLONE TEBUTATE
Dosage form(s): INJECTION Strength(s): 20mg/ml M anufacturers: ALP, FOY, RBP, M CK Category: B
PROBENECID W/ COLCHICINE
Dosage form(s): TABLET Strength(s): 500mg/0.5mg M anufacturers: DAN, LEM , M CK, RIC, ZGP Category: B
MASSACHUSETTS ADDITIONAL LIST OF INTERCHANGEABLE DRUGS
PROM ETHAZINE HCl
Dosage form(s): TABLET Strength(s): 12.5mg, 25mg, 50mg M anufacturers: ALL, ALT, ALP, DAN, ESR, GEV, KNO, KVN, LEM , LIF, M SM , RPC, S/W, W-A Category: B
PROPYLTHIOURACIL
Dosage form(s): TABLET Strength(s): 50mg M anufacturers: ANA, KNO, CHE, DAN, LIL, HAL, LAN, LED, P/D, PUR, RIC, TAB, W-W, ZEN Category: B
PSEUDOEPHEDRINE HCl
Dosage form(s): LIQUID Strength(s): 30mg/5ml
TABLET 30mg, 60mg SUSTAINED RELEASE CAPSULE 120mg
M anufacturers: ALP, BOW, GLW, CEN, CHE, GEV, DAN, HAL, RBP, LEM , M M D, PAR, ROX, SLV, SUP Category: OTC
PSEUDOEPHEDRINE HCl, CHLORPHENIRAM INE M ALEATE
Dosage form(s): TABLET Strength(s): 60mg/4mg M anufacturers: BER, GLW, ROR, SCH, SKB Category: OTC
PSEUDOEPHEDRINE SULFATE, DEXBROM PHENIRAM INE M ALEATE
Dosage form(s): SUSTAINED RELEASE TABLET Strength(s): 120mg/6mg M anufacturers: COP, GEV, SCH Category: OTC
QUININE SULFATE
Dosage form(s): TABLET Strength(s): 260mg M anufacturers: CHE, GEV, M M D Category: PRE-38
RAUWOLFIA SERPENTINA
Dosage form(s): TABLET Strength(s): 50mg, 100mg M anufacturers: BOW, CM B, GEV, DAN, FER, HAL, ICN, KIR, PAN, PPI, PRI, BM S, SLV, RIC, TAB,
VAL, ZEN
Category: B
RESERPINE
Dosage form(s): TABLET Strength(s): 0.1mg, 0.25mg, 0.5mg, 1.0mg
INJECTION
M anufacturers: BEL, BM S, BOW, CM B, GEV, DAN, FER, GEI, GEN, HAL, ICN, , KIR, LAN, LEM , LIL,
M KL, M YL, PAN, PRV, PRI, PUR, SLV, REX, RIC, ROX, STL, TAB, P/U, VAL, ZEN
Category: B
SALSALATE
Dosage form(s): TABLET Strength(s): 500mg, 750mg M anufacturers: GEV, 3M P, SID Category: Pre-38
SODIUM FLUORIDE
Dosage form(s): TABLET Strength(s): 0.55mg, 1.1mg, 2.2mg (NaF)
DROPS 0.125mg (F-)/DROP CHEWABLE TABLET 0.55mg, 1.1mg, 2.2mg (NaF)
M anufacturers: ABL, KNO, BOW, CHE, CM C, COP, C-P, GEN, HOY, KIR, RIC, RUG, STL, Category: PRE-38
SULFAM ETHOXAZOLE, PHENAZOPYRIDINE HCl
Dosage form(s): TABLET Strength(s): 500/100mg M anufacturers: COP, RIC Category: DESI
SULFASALAZINE
Dosage form(s): ENTERIC COATED TABLETS Strength(s): 500mg M anufacturers: DAN, LED, LEM , M UT, KBP, ROW, SUP, VIP Category: B
MASSACHUSETTS ADDITIONAL LIST OF INTERCHANGEABLE DRUGS
SULFISOXAZOLE PHENAZOPYRIDINE HCl
Dosage form(s): TABLET Strength(s): 500/50mg M anufacturers: COP, KAY, ROC, ROX, SLV, S-M , STN, VAN, Category: DESI
TERBUTALINE SULFATE
Dosage form(s): TABLET Strength(s): 2.5mg, 5mg M anufacturers: GEI, M M D Category: B
TESTOSTERONE
Dosage form(s): INJECTION Strength(s): 25mg/ml, 50mg/ml, 100mg/ml M anufacturers: BAT, STS,RBP, LIL, M AY Category: PRE-38
TETRACAINE HCl
Dosage form(s): OPHTHALM IC SOLUTION Strength(s): 0.5% M anufacturers: ALC, GEN, B&L, S-M , S/W Category: PRE-38
THEOPHYLLINE (NON-SUSTAINED RELEASE)
Dosage form(s): CAPSULE Strength(s): 100mg, 200mg
TABLET 100, 125, 200, 225, 250mg
M anufacturers: ALP, BEL, BER, CNC, CTL, FER, HAL, KNO, LAN, LIF, M M D, PAN, P/A, RIC, 3M P,
ROR, ROX, RPC, SEA,
Category: B
THEOPHYLLINE, GUAIFENESIN
Dosage form(s): ELIXIR Strength(s): 150mg/90mg/15ml
LIQUID
M anufacturers: M EA, RPC Category: PRE-38
THEOPHYLLINE, POTASSIUM IODIDE (THEOPHYLLINE, POTASSIUM IODIDE, ALCOHOL)
Dosage form(s): ELIXIR Strength(s): 80mg/130mg/10%/15ml M anufacturers: FOR, ALP, RPC Category: PRE-38
THYROGLOBULIN
Dosage form(s): TABLET Strength(s): 65mg M anufacturers: RIC, P/D, W-L Category: B
TRIAM CINOLONE DIACETATE
Dosage form(s): INJECTION Strength(s): 25mg, 40mg/ml M anufacturers: BM S, LED, LEM , STS Category: B
TRICHLORM ETHIAZIDE, RESERPINE
Dosage form(s): TABLET Strength(s): 4mg/0.1mg M anufacturers: M M D, SCH Category: B
TRIPROLIDINE HCl, PSEUDOEPHEDRINE HCl
Dosage form(s): TABLET Strength(s): 2.5mg/60mg
SYRUP 1.25mg/30mg/5ml
M anufacturers: GLW, ALP, CHE, CNC, GEV, HAL, ICN, LED, LEM , LIF, NEW, B&L, PRI, PUR, ROX,
SLV, SUP, VAN, ZEN
Category: OTC
TRYPSIN, BALSAM PERU, CASTOR OIL
Dosage form(s): TOPICAL AEROSOL Strength(s): 0.1mg/72.5mg/650mg IN EACH
0.82CC SPRAY
M anufacturers: COP, HIC Category: PRE-38
PARTIAL PROPRIETARY BRAND CROSS-REFERENCE
Generically equivalent drug products in the same strength and dosage form listed in the Additional List are interchangeable if their respective manufacturers are listed for that product. This partial cross- reference section does not attempt to list all brand names which are approved for interchange. For most products only one, usually the innovator or most commonly prescribed brand, is listed below for quick reference purposes. See page 4105 for precise instructions for determining the interchangeability of drug products.
BRAND SEE
(ATROPINE SULFATE, HYOSCINE HBr, HYOSCYAM INE HBr, PHENOBARBITAL)
(THEOPHYLLINE, POTASSIUM IODIDE, ALCOHOL)
ACTIFED . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TRIPROLIDINE HCl, PSEUDOEPHEDRINE HCl ANDROID . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . M ETHYLTESTOSTERONE
ANTABUSE DISULFIRAM
AQUAM EPHYTON . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PHYTONADIONE AURALGAN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . BENZOCAINE, ANTIPYRINE AZO-GANTANOL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . SULFAM ETHOXAZOLE, PHENAZOPYRIDINE AZO-GANTRISIN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . SULFISOXAZOLE PHENAZOPYRIDINE HCl AZULFADINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . SULFASALAZINE BENADRYL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DIPHENHYDRAM INE HCl
CYANOCOBALAM IN
BICILLIN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PENICILLIN G BENZATHINE BRETHINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TERBUTALINE SULFATE CHLOR-TRIM ETON . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . CHLORPHENIRAM INE M ALEATE COL-BENEM ID . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PROBENECID W/ COLCHICINE
CYCLANDELATE
DECADRON . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DEXAM ETHASONE DESQUAM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . BENZOYL PEROXIDE DIM ETANE DX . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . BROM PHENIRAM INE, DEXTROM ETHORPHAN, PSEUDOEPHEDRINE DIUPRESS . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . CHLOROTHIAZIDE W/ RESERPINE DONNATAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ATROPINE SULFATE COM POUND DRAM AM INE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DIM ENHYDRINATE DRIXORAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (product reformulated) ECONOPRED . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PREDNISOLONE ACETATE ELIXOPHYLLINE KI . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . THEOPHYLLINE, POTASSIUM IODIDE EM PIRIN W/ CODEINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ASPIRIN W/ CODEINE PHOSPHATE ESTINYL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ETHINYL ESTRADIOL EXNA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . BENZTHIAZIDE FEDAHIST . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PSEUDOEPHEDRINE HCl, CHLORPHENIRAM INE M ALEATE GLAUCON . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . EPINEPHRINE HCl GRANULEX . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TRYPSIN, BALSAM PERU, CASTOR OIL HALOTESTIN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . FLUOX\YM ESTERONE HYCOM INE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . HYDROCODONE BITARTRATE W/ PHENYLPROPANOLAM INE HYDROPRES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . HYDROCHLOROTHIAZIDE W/ RESERPINE ISOPTO CARPINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PILOCARPINE HCl ISORDIL TEM BID . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ISOSORBIDE DINITRATE ISUPREL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ISOPROTERENOL HCl KAON . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . POTASSIUM GLUCONATE KENALOG . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TRIAM CINOLONE DIACETATE LARODOPA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . LEVODOPA LEVSIN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . L-HYOSCYAM INE SULFATE LIBRAX . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . CHLORDIAZEPOXIDE W/CLIDINIUM BROM IDE M ANDELAM INE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . M ETHENAM INE M ANDELATE M EBARAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . M EPHOBARBITAL M ENEST . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ESTROGENS, ESTERIFIED M ETALONE T.B.A . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PREDNISOLONE TEBUTATE M ICRONASE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . GLYBURIDE
M AGNESIUM SALICYLATE
NEO-SYNEPHRINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PHENYLEPHRINE HCl
BRAND SEE
CHLORAL HYDRATE
PAM ELOR . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . NORTRIPTYLINE HCl PHENERGAN PLAIN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PROM ETHAZINE HCl PONTOCAINE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TETRACAINE HCl PROSED . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . M ETHENAM INE COM BINATION (M ETHENAM INE, PHENYLSALICYLATE,
ATROPINE SULFATE, HYOSCYAM INE, BENZOIC ACID M ETHYLENE BLUE)
PROSTIGM INE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . NEOSTIGM INE M ETHYLSULFATE PYRIDIUM . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PHENAZOPYRIDINE HCl QUINAM M . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . QUININE SULFATE SALUTENSIN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . HYDROFLUM ETHIAZIDE, RESERPINE SANOREX . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . M AZINDOL SERAPES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . HYDRALAZINE HCl, HYDROCHLOROTHIAZIDE, RESERPINE SLO-PHYLLIN GG . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . THEOPHYLLINE, GUAIFENESIN SLO-PHYLLIN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . THEOPHYLLINE (NON-SUSTAINED RELEASE) SSKI . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . POTASSIUM IODIDE SUDAFED . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . PSEUDOEPHEDRINE HCl SYNTHROID . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . LEVOTHYROXINE SODIUM TENUATE . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DIETHYLPROPION HCl
TESTOSTERONE
TUINAL . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . AM OBARBITAL SODIUM , SECOBARBITAL SODIUM VASODILAN . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ISOXSUPRINE
(PAGES 4127 THROUGH 4132 ARE RESERVED FOR FUTURE USE.)