1. a) The efficacy and usefulness of the soil amendment if applied in this State at the amount and frequency recommended by the applicant.
2. b) The truthfulness of any statement made on the proposed soil amendment label or in a registration or amended registration application.
3. c) The Department shall require that the substantiation include replicable results of controlled experimental studies using the soil amendment, the names and qualifications of the researchers performing the studies and a complete description of the conditions and additional information concerning procedures of the studies.
4. d) The Department may request assistance from any source in evaluating any substantiating evidence.

As a condition to the issuance of a registration or amended registration the Department shall require that the applicant substantiate by scientific evidence: