Cal. Code Regs. tit. 8, § 47
(b) For all claims having dates of injury on or after January 1, 2005, and for those compensable claims arising before January 1, 2005, where there has been either no comprehensive medical-legal report or no report by a treating physician indicating the existence of permanent disability, or when the employer is not required to provide the notice required by section 4061 to the injured worker, the method of measuring the immunological elements of impairment shall be described in the American Medical Association, Guides to the Evaluation of Permanent Impairment [Fifth Edition] (AMA Guides). Permanent disability shall be described by applying the provisions of the Permanent Disability Rating Schedule adopted by the Administrative Director pursuant to section 9805 of Title 8 of the California Code of Regulations.
STATE OF CALIFORNIA
GRAY DAVIS, GOVERNOR
DEPARTMENT OF INDUSTRIAL RELATIONS
Industrial Medical Council
395 Oyster Point Boulevard, 1st Floor, Wing C
ADDRESS REPLY TO:
South San Francisco, CA 94080
P.O. Box 8888
San Francisco, CA 94128-8888
Guidelines For Immunologic Testing Adopted March 17, 1994
Laboratory testing of immunologic function is appropriate and necessary in the evaluation of industrial injuries but only in selected cases.
Immunologic function testing falls into four general categories:
IV. Specific infection.
Category I: Allergy To A Specific Chemical Agent
Testing shall be done only when:
C. The specific suspected chemical agent of interest has been identified.
Testing shall not be done for chemical agents to which the worker has not been exposed.
The purpose of Category I is to confirm that the worker is allergic and reactive to a specific chemical agent. The presence of a laboratory test showing reactivity does not in itself indicate physical disability unless there also are subjective symptoms and/or objective findings of physical impairment which are consistent with such reactivity. Many people have positive reactivity tests but do not have clinical disease. Testing methods must be for the specific chemical agent. They may be blood tests for antibodies, skin tests or special tests such as lymphocyte reactivity to beryllium.
Category II: Tendency To React To Common Allergens
This testing is of very limited use: It is allowable only when the clinical findings (e.g., sneezing, nasal obstruction or wheezing) could be due to either workplace agent or non-industrial exposure. Testing may be of the blood (IgE, RAST) or of the skin (patch, scratch or intradermal).
Category III: Testing Of Function Of The Immune System
In unusual circumstances (e.g., occupational exposures to ionizing radiation or chemotherapeutic agents), direct clinically significant damage to the immune system may occur and be relevant to the assessment of occupationally related disability. Many chemical agents other than chemotherapeutic drugs have been shown to produce subtle effects on the immune system in research studies. However, such subtle effects do not cause work-related disability and cannot be the basis for laboratory testing.
In the unusual circumstance in which the need for immune testing occurs, such testing shall involve some or all the following:
C. Total lymphocyte count and counting of T and B lymphocytes, including subsets.
Further testing of the immune system must be based on a strong clinical indication and must be supported by an explanation by the physician as to the need and purpose of the testing (which may be diagnostic or prognostic in nature but not for research purposes).
Under circumstances such as a severely emotionally stressful event or the taking of certain medications for an industrial illness or injury, an autoimmune disorder may be precipitated or aggravated. When symptoms and/or physical findings suggestive of this occur, serological testing for autoimmune disorders is appropriate, but only when needed to confirm the diagnosis.
Category IV: Specific infections
Serologic and other immune system testing are allowable only when the physician-obtained history, physical examination, routine laboratory test results and/or medical records confirm or cause the physician to suspect certain infections that may be occupationally-related (e.g., viral hepatitis, valley fever and HIV infection).
Testing may be specific for the infectious agent or may be nonspecific:
A. Specific tests:
B. Nonspecific tests:
2. Total lymphocyte count and counting of T and B lymphocytes, including subsets. Further testing of the immune system shall be based on strong clinical indications and shall be supported by an explanation by the physician of the need and purpose of the testing.
SUMMARY:
In the four selected categorical situations, immunological laboratory testing is appropriate only as described above. Such testing shall be performed in Workers' Compensation cases only if an abnormality would affect the determination of compensability or clinical management. These conditions include determination of disability status (temporary partial disability, temporary total disability, permanent partial disability and permanent total disability), specific work restrictions, causation of disability, apportionment, future medical treatment and the need for vocational rehabilitation.
Note: Authority cited: Section 139.2(j)(2), Labor Code. Reference: Sections 139.2(j)(2), 4060, 4061 and 4062, Labor Code.
1. New section filed 5-23-94; operative 6-22-94 (Register 94, No. 21).
2. Amendment of Note filed 4-14-2000; operative 5-14-2000 (Register 2000, No. 15).
3. Change without regulatory effect amending section filed 7-12-2001 pursuant to section 100, title 1, California Code of Regulations (Register 2001, No. 28). Pursuant to this filing, material adopted pursuant to the Administrative Procedure Act that had previously been incorporated by reference in the California Code of Regulations was instead printed in full in the California Code of Regulations.
4. Amendment filed 1-13-2009; operative 2-17-2009 (Register 2009, No. 3).