Cal. Code Regs. tit. 3, § 6172 – General Toxicity Data.

(a) The following data shall be submitted with every application for registration.
1. (1) Acute oral and dermal LD₅₀ data on the product.
2. (2) Acute LC₅₀ data on products which produce a respirable aerosol or gas.
3. (3) Primary eye and skin irritation data on the product.
(b) The following data in addition to the data required by (a), (1)-(3) shall be submitted with each application to register a product containing an active ingredient not previously registered when required by the U.S. EPA to support the full unconditional registration pursuant to Section 3 of the Federal Insecticide, Fungicide and Rodenticide Act. Pesticides which are determined to be biorational pesticides as determined by the director, may be exempted from the chronic toxicity data requirements.
1. (1) Results of a two-year feeding study for oncogenicity on active ingredients in two animal species.
2. (2) Results of a teratogenicity study and a two-generation combined male-female reproductive study on active ingredients.
3. (3) Results of three mutagenicity studies on active ingredients that detect gene mutations, chromosomal aberrations, and DNA damage/repair.

Note: Authority cited: Sections 12781 and 12824, Food and Agricultural Code. Reference: Sections 11501 and 12824-12825, Food and Agricultural Code.

History

1. Editorial renumbering of former Section 2379.5 to Section 6172 filed 7-19-85 (Register 85, No. 29).

2. Amendment filed 6-29-87; operative 7-29-87 (Register 87, No. 31).

3. Change without regulatory effect amending subsection (b) and Note filed 3-27-97 pursuant to section 100, title 1, California Code of Regulations (Register 97, No. 13).

4. Change without regulatory effect amending subsections (a)(1), (a)(3) and (b) filed 8-14-2002 pursuant to section 100, title 1, California Code of Regulations (Register 2002, No. 33).

5. Change without regulatory effect amending subsections (a)(1) and (a)(3) filed 2-7-2007 pursuant to section 100, title 1, California Code of Regulations (Register 2007, No. 7).

6. Amendment of subsections (a)(1) and (a)(3) filed 2-8-2007; operative 3-10-2007 (Register 2007, No. 7).