1. (a) United States Department of Health and Human Services select.

   Permissible Toxin Amounts HHS Toxins	Amount
   Abrin	100.0 mg
   Botulinum neurotoxins	0.5 mg
   Clostridum prefringens epsilon toxin	100.0 mg
   Conotoxins	100.0 mg
   Diacetoxyscirpenol	1,000.0 mg
   Ricin	100.0 mg
   Saxitoxin	100.0 mg
   Shigatoxin	100.0 mg
   Shi-like ribosome inactivating proteins	100.0 mg
   Staphylococcal entertoxins	5.0 mg
   Tetrodotoxin	100.0 mg
   T-2 toxin	1,000.0 mg

2. (b) Overlap agents and toxins.

   1. (1) Except for exclusions under paragraphs (d) and (e) in the Federal Register, the United States Secretary of Health and Human Services has determined that the biological agents and toxins listed below have the potential to pose a severe threat to public health and safety.
   2. (2) See rule 73.3 United States Department of Health and Human Services select agent and toxin for further information. Abrin Cecopithecine herpes virus 1 (Herpes B virus) Coccidioides posadasii Crimean-Congo hemorrhagic Fever virus Diacetoxyscirpenol Ebola Virus Lassa fever viruses Marburg virus Monkey pox virus Reconstructed replication competent forms of the 1918 pandemic influenza virus containing any portion of the coding regions of all eight (8) gene segments Ricin Rickettsia Prowazekii Rickettsia rickettsi Saxitoxin Shiga-like ribosome inactivating proteins South American Hemorrhagic Fever Viruses (Junin, Machupo, Sabia, Flexal, Guanarito) Tetrodotoxin Tick-borne encephalitis complex (flavil) viruses (Central European Tick- borne encephalitis, Far Eastern Tick-borne encephalitis, Russian Spring and Summer encephalitis, Kyasanur Forest disease, Omak hemorrhage Fever) Variola major virus (Smallpox virus) and Vaiola minor virus (Alastrim) Yersinia pestis.
3. (c) Except for exclusions under paragraph (d) and (e) the Federal Register the secretary has determined that the biological agents and toxins listed below have the potential to pose a severe threat to public health and safety, to animal health, or to animal product.
4. (d) Overlap select agents and toxins. See Rule 73.4 for further information. Bacillus anthracis Botulinum neurotoxins Botulinum neurotoxin-producing species of Clostridium Brucella abortus Brucella melitnesis Brucella suis Burkholderia pseudomalleia (formerly Pseudomonas) Burkholderia pseudomallei (formerly Pseudomonas pseudomallei) Clostridium perfringens epsilon toxin Coccidioides immitis Coxiella burnetii Eastern Equine Encephalitis virus Francisella tularensis Hendra virus Nipah Virus Rift Valley fever virus Shigatoxin Staphylococcal enterotoxins T-2 toxin Venezuelan Equine Encephalitis virus.

Codification Notes: 73.3 can be found at 42 C.F.R. § 73.3. Rule 73.4 can be found at 42 C.F.R. § 73.4.