OPINION
Shirley F. Crowell, Alan Julian and Lora G. Horner appeal from the sentences imposed upon them after their convictions of conspiracy and possession with intent to distribute dilaudid, a prescription drug which contains hydromorphone, a Schedule II controlled substance. 21 U.S.C. §§ 841(a), 846. The single question we address in this opinion is whether the district court shall use the gross weight of the dilaudid tablet, or only the net weight of the controlled substance hydromorphone, in calculating drug quantity for purposes of sentencing. 1 We conclude that the district court properly based its calculation on the gross weight of the dilau-did tablets and affirm on this issue.
BACKGROUND FACTS
In 1988, the Drug Enforcement Agency began investigating several persons who were illegally trafficking in dilaudid. Dilau- *1453 did is a pharmaceutically manufactured pain killer which produces effects similar to heroin’s. DEA agents surveilled Horner and other members of the conspiracy as they visited doctors in California, Arizona and New Mexico and obtained multiple prescriptions for dilaudid under false pretenses. The tablets were transported to Julian and Cro-well in Tennessee and to other conspirators in Missouri for resale.
Horner, Julian and Crowell were convicted by a jury of conspiracy and of several counts of possession with intent to distribute dilau-did in violation of 21 U.S.C. §§ 841(a), 846. The district court found that Horner entered the conspiracy on June 1, 1990, and that she was accountable, pursuant to United States Sentencing Commission, Guidelines Manual, § 1B1.3 (Nov. 1990), 2 for 11,790 dilaudid tablets distributed by the conspiracy between June and November 1990. Based on a gross weight of 90 milligrams per tablet, the district court calculated the drug quantity to be 1,061 grams of dilaudid, which was equivalent to 2,662 kilograms of marijuana. That drug quantity placed the offense level at 32. U.S.S.G. § 2Dl.l(e)(6). Horner had a criminal history category of I, which resulted in a Guideline range of 121 to 151 months.
Horner objected to the calculation. She argued that only the weight of the controlled substance should be considered. Each dilau-did tablet contained 4 milligrams of hydro-morphone. Using only the amount of hydro-morphone, Homer calculated the total drug quantity to be 47 grams of hydromorphone, the equivalent of 117 kilograms of marijuana, which resulted in an offense level of 26 and Guideline range of 63 to 78 months. The district court rejected this argument and sentenced Horner at the lowest point on the higher Guideline range, 121 months.
Julian and Crowell were held accountable for 19,198 dilaudid tablets distributed by the conspiracy between January and November 1990. Using the gross weight of the tablets, the district court calculated the drug quantity to be 1,729 grams of dilaudid, which was equivalent to 4,324 kilograms of marijuana. That placed the drug quantity at level 34. Julian and Crowell each had a criminal history category of I, which resulted in a sentencing range of 151 to 188 months. The district court sentenced Julian to 155 months, and sentenced Crowell to 151 months. Neither Julian nor Crowell objected to the drug quantity calculation in the district court.
JURISDICTION AND STANDARD OF REVIEW
The district court had jurisdiction pursuant to 18 U.S.C. § 3231. Our jurisdiction to review the sentence is based on 18 U.S.C. § 3742(a). “A district court’s interpretation and application of the sentencing guidelines are reviewed de novo.”
United States v. Conkins,
DISCUSSION
We must first address whether appellants are entitled to press their claims on appeal. Horner filed a written objection to the Pre-sentence Report in which she challenged the probation officer’s calculation of drug quantity based on the gross weight of the dilaudid tablets, rather than on the net weight of the hydromorphone. Although Horner did not argue this legal question at the sentencing hearing, the district court did consider and overrule Horner’s objections to the Presen-tence Report. Julian and Crowell, however, did not make any objection to the calculation of drug quantity, either through objection to the Presentence Reports or at the sentencing hearing.
Ordinarily, this court “will not consider an issue raised for the first time on appeal.”
United States v. Mondello,
Section 841(b)(1) of Title 21 governs sentences for the distribution of controlled sub
*1454
stances. Subsections (A), (B) and (D), which apply to certain enumerated controlled substances, specifically link the quantity of the controlled substance to the term of imprisonment. Dilaudid falls within § 841(b)(1)(C), which authorizes a term of imprisonment of not more than 20 years. Subsection (C) does not address how, or whether, the sentence is related to the weight of the controlled substance. As the District of Columbia Circuit Court of Appeals noted, § 841(b)(1)(C) permits a sentence of 20 years for “distribution of
any
amount of hydromorphone, even a single dosage.”
United States v. Shabazz,
That statutory gap is addressed by the Sentencing Guidelines. The general Guideline principle is that drug quantity includes the entire weight of any mixture containing a detectable amount of controlled substance. U.S.S.G. § 2D1.1 n. * & comment, (nn. 10 & 11). Dilaudid is a mixture of inert ingredients and hydromorphone, a controlled substance.
Shabazz,
Appellants contend that use Of the gross weight of the tablet contravenes the market-oriented approach of
Chapman v. United States,
We find that use of the gross weight of the tablet is
entirely
consistent with
Chapman.
The market-oriented approach does not turn on the ability to dilute the drug. The essence of that approach is that the retail dealer is punished based on the number of doses he distributes.
See
500 U.S. at-,
Appellants also insist that we should be guided by
United States v. Robins,
Finally, appellants argue that 21 U.S.C. § 841(b)(1)(C) and U.S.S.G. § 2D1.1 are ambiguous and the rule of lenity requires that they be interpreted to apply only to the weight of the hydromorphone. This argument has been rejected as well.
Chapman,
500 U.S. at-,
The rule of lenity, however, is not applicable unless there is a grievous ambiguity or uncertainty in the language and structure of the Act, such that even after a court has seized every thing from which aid can be derived it is still left with an ambiguous statute. The rule of lenity comes into operation at the end of the process of construing what Congress has expressed, not at the beginning as an overriding consideration of being lenient to wrongdoers.
500 U.S. at-,
CONCLUSION
The Guidelines provide that for sentencing purposes the entire weight of a mixture containing a controlled substance will be treated as the weight of the controlled substance itself. Pills are just that — a controlled substance mixed with other ingredients. There is no reason to treat them differently from other methods of delivering drugs to their ultimate consumers. Thus, the district court properly calculated the drug quantity based on the entire weight of the dilaudid tablets.
AFFIRMED on the issue decided in this opinion. However, the sentences of Julian and Crowell are VACATED for the reasons set forth in our unpublished memorandum disposition which is filed on this date.
