Defendants-appellants Multidata Systems International Corp., MDS Inc., MDS (Canada) Inc., and MDS Nordion Inc. (collectively “Defendants”) appeal the district court’s interlocutory order refusing to dismiss this case: (1) for lack of personal jurisdiction; (2) as barred by the doctrines of res judicata and direct estoppel; and (3) *605 for forum non conveniens. Because we find that Texas cannot exercise general jurisdiction over Defendants, and the plaintiffs-appellants (“Plaintiffs”) do not allege that specific jurisdiction exists, we reverse the district court’s order. We do not consider the remaining issues.
I.
This is the third suit that Plaintiffs have brought in the United States against Defendants, Multidata Systems International Corp. (“Multidata”), a Delaware corporation with its principal place of business in St. Louis, Missouri, and three Canadian corporations, MDS Inc. (“MDS”), MDS (Canada) Inc. (“MDS Canada”), and MDS Nordion Inc. (“MDS Nordion”), for personal injuries to themselves or their decedents. Plaintiffs or their decedents were cancer patients who received radiation therapy at the Instituto Oncológico Na-cional (“ION”) in Panama City, Panama, between August and December 2000. During this time, they were over-exposed to radiation, resulting in serious injuries and several deaths. Most of the plaintiffs are citizens and residents of Panama, although Plaintiffs claim that six of the surviving representatives are citizens or authorized residents of the United States. Not one of the injured plaintiffs or decedents is a Texas resident.
Plaintiffs or their decedents were treated at ION with a Theratron 780C Teleth-erapy Unit (“Theratron Unit”) in conjunction with a Treatment Planning System (“TPS”). The Theratron Unit is a cancer-treating radiation device that delivers therapeutic Cobalt radiation to cancer patients. It was originally designed and manufactured by Theratronics International Ltd. (“Theratronics”), a Canadian corporation. The unit in use at ION was, in fact, sold by Theratronics in 1992. In 1998, however, the Canadian Development Investment Corporation sold Theratronics to MDS, which, in turn, sold Theratronics to its wholly-owned subsidiary, MDS Nor-dion. In 2001, MDS Nordion ceased to exist as a corporate entity when it merged with MDS Pharma Services, Inc., another wholly-owned subsidiary of MDS, to form MDS Canada.
The TPS, meanwhile, is a stand-alone computer and software system manufactured by Multidata. It is used to assist physicists in calculating radiation dosages, distribution, and treatment times for cancer patients. The TPS considers numerous factors in making its calculations, including the prescription from the doctor, the distance the patient is located from the radiation source, the depth of the tumor being treated, and the number of “shielding blocks” used in conjunction with the radiation treatment. A shielding block is a material designed to shape the radiation beam to protect a patient’s healthy organs and sensitive tissue. The TPS was designed to perform calculations using up to four shielding blocks.
In or around August 2000, one of the radiation oncologists at ION requested a treatment plan that used five shielding-blocks. Although the TPS was not designed to calculate the proper level of radiation dosages under such circumstances, ION doctors and physicists determined that they could manipulate the data entry procedure by making it appear that five shielding blocks were actually one shielding block. Unfortunately, when the data was entered into the TPS using this new method, the dose calculation was incorrect. As a result, an over-dosage of radiation was prescribed, sometimes in excess of twice the amount of radiation that should have been administered.
Once the effects of the over-radiation surfaced, the government of Panama requested separate investigations by the In *606 ternational Atomic Energy Association (“IAEA”) and a group of physicians and physicists from M.D. Anderson Cancer Center (“M.D. Anderson”) in Houston, Texas. Both the IAEA and the M.D. Anderson doctors published reports explaining their understanding of the events leading to the over-radiation. Both reports concluded that the patients received excess radiation because the TPS was erroneously re-configured to calculate the amount of radiation necessary when using five shielding blocks. In addition, the ION doctors and physicists were faulted for failing to: (1) manually verify the TPS’s calculations; or (2) simulate treatment plans by irradiating a water phantom and measuring the dosage. Moreover, ION staff were faulted for failing to compare the newly calculated dosage levels to similar prior treatments and failing to detect early symptoms of excessive radiation exposure in the patients being over-exposed to radiation by the new treatment plan.
Ultimately, as a result of these and other investigations, the ION doctors and physicists that caused Plaintiffs’ over-radiation were sanctioned or prosecuted to varying degrees by the Panamanian government. An ION radiation oncologist and three physicists lost their licenses to practice medicine in Panama. In addition, two of the three physicists were criminally convicted in Panama of negligent homicide.
On October 17, 2001, Plaintiffs filed a lawsuit in the Circuit Court of the County of St. Louis, Missouri, against Defendants. Plaintiffs alleged that they suffered from the effects of excess radiation because the Theratron Unit and TPS were defective. They sought damages for wrongful death and negligence. Defendants immediately moved for dismissal on forum non conve-niens grounds, arguing that the case should be heard in Panama where most of Plaintiffs lived, where the Plaintiffs or their decedents were injured, and where most of the witnesses and evidence were located. Plaintiffs responded that Missouri was a convenient forum because Multidata was located there. Moreover, Plaintiffs argued that Panama was not an available alternative forum because: (1) Panama’s judicial system was corrupt; and (2) Panama would not accept jurisdiction over a case previously dismissed from a foreign jurisdiction. After permitting discovery, the state trial court held a three day evidentiary hearing to determine whether the action should be dismissed. Both Plaintiffs and Defendants presented expert testimony concerning the availability of Panama as an alternative forum.
Before the Missouri trial court reached a decision, however, one of the Plaintiffs filed a petition in the San Miguelito Judicial District Court of Panama against Defendants. Before Defendants were served with the petition or otherwise notified of the filing, the Panamanian court dismissed the case for want of jurisdiction. Plaintiffs notified the Missouri trial court of this outcome and sought to rely on the dismissal from the Panamanian court to prove that Panama was not an available alternative forum. Defendants objected to the consideration of the ruling, claiming that the case was filed in the wrong venue and that they were never given the opportunity to waive jurisdictional defects.
On January 8, 2004, the Missouri trial court granted Defendants’ motion to dismiss without prejudice in a brief order on forum non conveniens grounds. The state trial court explicitly ruled that Plaintiffs could re-file in Missouri if Panama refused jurisdiction, stating:
[rjeconsideration may be given to the refiling of this cause in this jurisdiction if a determination is made by a Panamanian court of competent jurisdiction and venue for this cause that jurisdiction *607 does not exist in Panama and the Defendants were given the opportunity to submit to the jtirisdiction of the Panamanian court or were given notice of such filing so as to be able to present their position to the court on the issue of jurisdiction.
Chandler v. Multidata Sys. Int’l Corp., No. 01CC-3634, slip op. at 2 (Mo.Cir.Ct. Jan. 8, 2004) (emphasis added).
Plaintiffs appealed the state trial court’s decision to the Missouri Court of Appeals for the Eastern District of Missouri. On May 10, 2005, the Missouri Court of Appeals affirmed the decision in a published opinion.
Chandler v. Multidata Sys. Int’l Corp.,
Plaintiffs neither appealed to the Missouri Supreme Court nor re-filed in Panama. Instead, Plaintiffs filed four new cases in the Circuit Court of the County of St. Louis, Missouri. Plaintiffs argued that they had complied with the original Missouri court order because the Panamanian Court of Appeals subsequently affirmed the dismissal of the San Miguelito action. In response, Defendants moved to dismiss, arguing that they were not given the opportunity to be heard before the Panamanian trial court or to waive jurisdictional objections. On March 16, 2006, the four consolidated cases were dismissed by the Missouri trial court, which stated that:
Plaintiffs have not proven that this cause cannot be litigated in Panama. Plaintiffs have previously filed their claims in Panama and in this Court. Both jurisdictions dismissed the cases. Plaintiffs’ filing was not with the proper Panamanian Court. In addition, the law of the case doctrine herein, as well as, parts of the doctrine of res judicata apply to require plaintiffs to re-file these claims in Panama. If Panama refuses to proceed, the claims can be refiled in Missouri. Cause is dismissed without prejudice.
Navarro v. Multidata Sys. Int’l Corp., No. 05CC-3136, slip op. at 2 (Mo.Cir.Ct. Mar. 16, 2006).
On May 15, 2006, rather than filing in Panama, Plaintiffs filed the instant suit in the United States District Court for the Southern District of Texas, Galveston Division. 1 Plaintiffs’ claims were essentially the same as those brought in the Missouri state actions, including, amongst others, *608 counts for wrongful death and personal injuries caused by negligent design and manufacturing of the Theratron Unit and the TPS. On July 5, 2006, Defendants separately moved to dismiss the case for lack of personal jurisdiction, as barred by the doctrines of res judicata and direct estoppel, and on forum non conveniens grounds. Defendants argued that the case was barred because the Missouri state courts’ decisions precluded Plaintiffs from litigating the case in the United States. Before Plaintiffs filed a response, at an August 2, 2006, scheduling hearing, the district court ordered that discovery be conducted into the issues.
On February 9, 2007, after conducting discovery, Defendants re-moved to dismiss this case for lack of personal jurisdiction, as barred by the doctrines of res judicata and direct estoppel, and for forum non conveniens. In response, Plaintiffs argued that: (1) the district court could exercise general jurisdiction over Defendants; (2) the Missouri state courts’ decisions were not res judicata because the decisions merely prohibited Plaintiffs from re-filing in Missouri; and (3) the case could not be dismissed for forum non conveniens because Panama was not an available alternative forum.
On April 30, 2007, the district court denied the motions to dismiss without holding an evidentiary hearing, holding that Defendants had sufficient continuous and systematic contacts with Texas such that general jurisdiction existed. Moreover, the district court held that the Missouri trial courts’ dismissals for forum non con-veniens were not res judicata in a Texas federal court because the convenience of litigating the case in Missouri was different than the convenience of litigating the case in Texas. Finally, the district court refused to dismiss the case for forum non conveniens because Panama was no longer an available forum. On August 1, 2006, the Panamanian National Assembly had enacted Panamanian Assembly Law No. 32, chapter 4, § 2, article 1421-J (“Article 1421-J”), which stated that: “Lawsuits that are brought in the country as a result of a foreign judgment of forum non conveniens, impede national competence from being generated. Therefore, they must be rejected ex officio by reason of incompetence for constitutional order reasons or for preventive competence provisions.” (Translation by M. Delgado Deba-li, Certified Pub. Translator, Aug. 4, 2006). While the constitutionality of this law was immediately challenged by the Panamanian Attorney General in the Panamanian Supreme Court, a decision had not been rendered, and the district court was unwilling to overlook positive Panamanian law. 2
On May 14, 2007, Multidata and the Canadian defendants filed separate motions requesting that the district court certify portions of its April 30, 2007, order for interlocutory appeal under 28 U.S.C. § 1292(b), including the denial of Defendants’ motions to dismiss for lack of personal jurisdiction and as barred by the doctrines of res judicata and direct estop-pel. In addition, the Canadian defendants moved to certify the forum non conve-niens decision. Plaintiffs opposed the motions and, on July 11, 2007, the district court denied the motions because the “case [was] not momentous enough to justify an unwarranted intrusion into the [Fifth] Circuit’s time.” However, on November 14, 2007, the district court sua *609 sponte reconsidered the motions for interlocutory appeal, vacated the order denying the motions, and certified the April 30, 2007, order for immediate appeal. Accordingly, Multidata and the Canadian defendants filed petitions for permission to appeal with this court.
On December 12, 2007, a panel of this court granted the petitions. We need only consider the personal jurisdiction question to resolve the case.
II.
The plaintiff bears the burden of establishing a district court’s jurisdiction over a non-resident, but it need only make a prima facie case if the district court rules without an evidentiary hearing.
Wilson v. Belin,
A “federal court sitting in diversity may assert jurisdiction if (1) the state’s long-arm statute applies, as interpreted by the state’s courts; and (2) if due process is satisfied under the fourteenth amendment to the United States Constitution.”
Cycles, Ltd. v. W.J. Digby, Inc.,
“There are two types of ‘minimum contacts’: those that give rise to specific personal jurisdiction and those that give rise to general personal jurisdiction.”
Lewis v. Fresne,
“General jurisdiction can be assessed by evaluating contacts of the defendant with the forum over a reasonable number of years, up to the date the suit was filed.”
Access Telecom, Inc. v. MCI Telecomms. Corp.,
Before we apply these principles to this case, it is worthwhile to review past cases to illustrate just how difficult it is to establish general jurisdiction. The seminal general jurisdiction case is
Perkins v. Benguet Consolidated Mining Co.,
By contrast, in
Helicópteros,
the Supreme Court found that the defendant’s contacts with Texas were insufficient to support an exercise of general jurisdiction.
This circuit has consistently imposed the high standard set by the Supreme Court when ruling on general jurisdiction issues.
See, e.g., Cent. Freight Lines Inc. v. APA Transp. Corp.,
Moreover, in
Access Telecom,
we emphasized that in order to confer general jurisdiction a defendant must have a business presence
in
Texas.
In the instant case, it is quite clear that Multidata does not have sufficient systematic and continuous contacts with Texas to establish general jurisdiction. Plaintiffs put forward only three bases for jurisdiction. First, over a period of five years, Multidata sold approximately $140,000 worth of goods and related service contracts to ten different customers located in Texas. Those sales represented approximately three percent of Multidata’s business during that time span, and resulted in periodic trips by Multidata employees into Texas to service the equipment. Second, Multidata advertised in national trade journals whose circulation reached Texas. And, third, Multidata employees periodically attended trade conventions in Texas. In response, Multidata stresses that it neither maintains a place of business in Texas nor has a registered agent for service of process in Texas. It argues that the contacts identified by Plaintiffs are too limited and sporadic to give rise to general jurisdiction. We agree.
In
Alpine View Co. v. Atlas Copco AB,
we held that general jurisdiction did not exist where the “evidence show[ed], at
*612
best, that [the defendant] sold, on isolated occasions, products to entities located in Texas, ... that companies used [the defendant’s] products for projects in Texas, and that [the defendant’s] personnel made field visits to Texas between December 1992 and December 1993.”
Similarly, MDS’s contacts with Texas are lacking the substance or regularity necessary to establish general jurisdiction. Plaintiffs identify four different contacts that MDS has with Texas: (1) it purchased over $5.2 million worth of goods from Texas vendors during the five year period prior to the lawsuit; (2) it is party to a Hosting Services Agreement and a Software Licensing Agreement with a Texas corporation that is governed by Texas law; (3) it employs two Texas residents who perform work from their homes in Texas; and (4) a former corporate director lived in Texas. In response, MDS notes that it: (1) has not manufactured or sold any products in Texas; (2) owns no real property in Texas; (3) does not have a registered agent for service of process in Texas; and (4) does not maintain any offices in Texas. Moreover, it argues that the contacts identified by Plaintiffs are insufficient to establish a systematic and continuous contact with Texas. Once again, we agree.
First, the Supreme Court has already determined that purchases of goods from Texas vendors, standing alone, are not the type of contacts that will establish general jurisdiction.
See Helicópteros,
Nor are we convinced that MDS, which has not sold goods or services in Texas, has a general business presence in the state based on the residence of two employees and a former director. The two employees are Bill Lloyd, a product test manager in the area of product development, and Robert Deutschman, a software developer. Neither employee works with Texas customers. Both employees work from home and report to supervisors locat
*613
ed in Toronto, Canada. And both became employees through the happenstance of an acquisition, not because they resided in Texas. They were permitted to remain in Texas because they were able to perform their jobs anywhere in the world. While their presence is certainly a regular contact with Texas, it is not substantial enough to create a general business presence in Texas.
See
Access
Telecom,
MDS Canada’s contacts with Texas, although more substantial than the other defendants, also fail to create general jurisdiction. 3 Plaintiffs identify two major types of contacts. The first category is clinical trial work for pharmaceutical companies (referred to as “sponsors” by MDS Canada), which sometimes include contracts governed by Texas law. The clinical trial work at issue generally involves both in-house testing services and the coordination and design of trials carried out by independent physicians. MDS Canada’s contacts with Texas that arise from this work are twofold: (1) work done on behalf of Texas pharmaceutical companies; and (2) clinical trial work performed by independent physicians located in Texas, which is coordinated by MDS Canada. The record is unclear as to the total amount of money involved in these transactions. However, MDS Canada receives less than one percent of its testing revenue from Texas customers, and less than ten percent of its contracts with independent testing facilities are with doctors located in Texas.
The second category involves the sale of products and related services to Texas customers. The products include large and expensive medical equipment, such as Theratron units similar to the one at issue in this case, and Gammacell and Raycell irradiators, which sterilize donated blood to prevent the spread of disease through transfusions. MDS Canada has sold only a few of these items to Texas customers in the five years preceding this case. It sold no Theratron units (as opposed to one *614 hundred twenty-six worldwide) and only ten Gammacell and Raycell irradiators (as opposed to three hundred seventeen worldwide). On the other hand, MDS Canada also manufactures smaller and higher-volume products, including radioisotope devices that are used for medical imaging. It is unclear exactly how many of these products were sold to Texas customers. However, when added to the sale of the large radiation devices, and including customer service trips, MDS Canada sold a total $5,736,931, $1,494,263, $3,710,162, $6,164,747, and $8,751,805 worth of products to Texas customers in the years of 2002, 2003, 2004, 2005, and 2006, respectively. For four out of five years this accounted for 1.7%, 0.5%, 1.1%, and 2.5% of MDS Canada’s total global sales.
We do not believe that these various activities amount to substantial, systematic, and continuous contacts. MDS Canada is not registered to do business in Texas; does not own, possess or use property in Texas; does not maintain a mailing address or bank account in Texas; and does not keep, maintain or store any documents within Texas. While it is true that MDS Canada sells products and services to Texas customers, neither the total amount of sales nor the percentage of annual sales is substantial or regular enough to create a general presence in Texas.
See Access Telecom,
Nor do we find other less substantial contacts offered by Plaintiffs to affect our analysis. Plaintiffs note that MDS Canada sends its employees to Texas to service equipment. For example, in 2006, MDS Canada employees installed three machines, made nine services calls, and took approximately five trips into Texas for preventative maintenance. But as we noted above, mere travel, even at regular intervals into a state, does not create general jurisdiction.
See Helicópteros,
*615
We further believe that even if MDS Canada had continuous and systematic contacts with Texas (which, in our view, it does not), traditional notions of fair play and substantial justice would be violated if we exercised jurisdiction over it in this case. If the required minimum contacts are shown, jurisdiction exists unless the defendant can make a “compelling case” that traditional notions of fair play and substantial justice would be violated by the exercise of jurisdiction.
Wien Air Alaska, Inc. v. Brandt,
However, when foreign defendants are involved we must “consider the procedural and substantive policies of other
nations
whose interests are affected by the assertion of jurisdiction by the [forum state].”
Asahi Metal Indus. Co. v. Superior Court of Ca.,
as well as the Federal interest in Government’s foreign relations policies, [are] best served by a careful inquiry into the reasonableness of the assertion of jurisdiction in the particular case, and an unwillingness to find the serious burdens on an alien defendant outweighed by minimal interests on the part of the plaintiff or the forum State. “Great care and reserve should be exercised when extending our notions of personal jurisdiction into the international field.”
Id.
(citing
United States v. First Nat’l City Bank,
In
Asahi,
the Supreme Court held that jurisdiction would be unreasonable due to the burden on the foreign defendant.
Id.
at 116,
*616
The Court stressed that the burden placed on the Japanese corporation was severe because it was commanded to traverse the distance between its foreign headquarters and to submit itself to a foreign nation’s judicial system.
Id.
at 114,
Other circuit courts have since found that exercising jurisdiction over foreign defendants would be unreasonable under similar circumstances. For example, in
Ellicott Machine Corp. v. John Holland Party Ltd.,
Similarly, in
Benton v. Cameco Corp.,
Finally, in an analogous situation involving a domestic Delaware corporation, this court found it unreasonable for Texas to exercise jurisdiction even if the defendant’s contacts with Texas were systematic and continuous.
Beany,
In the instant case, we find that exercising jurisdiction over MDS Canada would offend traditional notions of fair play and substantial justice. First, like the defendant in
Asahi,
a severe burden would be placed on MDS Canada if it is forced to defend itself in Texas. In addition to the regular burdens of defending oneself in a foreign legal system, MDS Canada would not have compulsory access to many of the witnesses and evidence necessary to defend itself.
Cf. Electrosource, Inc. v. Horizon Battery Techs., Ltd.,
None of these factors is outweighed by an interest of Texas or Plaintiffs. First, the only manner in which Texas could be conceivably viewed as a more convenient forum than Panama is if we focus on the six Plaintiffs who reside in the United States. But more than two hundred remaining plaintiffs reside in Panama. Taken as a whole, Plaintiffs cannot establish that it would be more convenient for them to litigate this case in Texas.
Second, Texas has, at most, a minimal interest in adjudicating the dispute. None of the injured Plaintiffs was a Texas resident, MDS Canada’s allegedly tortious acts did not take place in Texas, Plaintiffs’ injuries did not occur in Texas, and Texas law does not govern the dispute.
See Reich v. Signal Oil & Gas Co.,
In sum, we do not believe that MDS Canada has sufficient substantial, continuous, and systematic contacts with Texas to justify the exertion of general jurisdiction. MDS Canada does not maintain any office or other permanent presence in Texas. And the volume of MDS Canada’s business in Texas is not so substantial that it should have reasonably expected to be haled into Texas court on any matter whatsoever. But even if MDS Canada’s contacts were sufficient, it would offend traditional notions of fair play and substantial justice to exercise jurisdiction over MDS Canada in this case. In light of the international context of the case, the slight interests of both Plaintiffs and Texas, it is unreasonable to impose the heavy burden of defending this case in Texas on MDS Canada.
See Asahi,
III.
For the reasons stated above, we REVERSE the district court’s April 30, 2007, order and REMAND with instructions to dismiss the ease without prejudice. Plaintiffs shall bear the costs of this appeal.
Notes
. On May 26, 2006, four of the plaintiffs finally re-filed their claims in a Panamanian Court, namely, the Judicial District Court for Panama City, Panama. Once again, however, the case was promptly dismissed, and Defendants were again unable to waive any jurisdictional defects because the petition was not served upon Defendants until after the suit was dismissed. Defendants allege that this lawsuit was dismissed because it was filed in the wrong venue and, below, argued that the petition was not filed in good faith because a large portion of it argued that the Panamanian court lacked any jurisdiction.
. During oral argument, we were informed that the Panamanian National Assembly has since repealed Article 1421-J. Because we decide this case on personal jurisdictional grounds, we do not have to weigh the effect of this repeal on our review of the district court’s res judicata or forum non conveniens decisions.
. For this reason, MDS Nordion, which merged with MDS Pharma Services, Inc., to form MDS Canada, also does not have sufficient contacts with Texas such as to create general jurisdiction.
See Engel v. Teleprompter Gap.,
